gpDB: a database of GPCRs, G-proteins, Effectors and their interactions
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gpDB::GPCR View
Entry 1 of 1 :: GPCR0188 ::
CLASS CLASS A (RHODOPSIN LIKE)
FAMILY ADENOSINE RECEPTOR
SUBFAMILY A2B

Cross References:
UniProt P29276 EMBL M91466
InterPro IPR001435 | IPR001634 | IPR000276 GPCRDB AA2BR_RAT
GENEID 29316
PRINTS PR00554 | PR00424 | PR00237 PFAM PF00001

Details:
NAME ADENOSINE RECEPTOR_A2B_Rattus norvegicus
DESCRIPTION Adenosine receptor A2b.
SPECIES Rattus norvegicus COMMON NAME Rat NCBI Taxonomy 10116
GENE Adora2b
SEQUENCE
MQLETQDALYVALELVIAALAVAGNVLVCAAVGASSALQTPTNYFLVSLATADVAVGLFA
IPFAITISLGFCTDFHSCLFLACFVLVLTQSSIFSLLAVAVDRYLAIRVPLRYKGLVTGT
RARGIIAVLWVLAFGIGLTPFLGWNSKDRATSNCTEPGDGITNKSCCPVKCLFENVVPMS
YMVYFNFFGCVLPPLLIMMVIYIKIFMVACKQLQHMELMEHSRTTLQREIHAAKSLAMIV
GIFALCWLPVHAINCITLFHPALAKDKPKWVMNVAILLSHANSVVNPIVYAYRNRDFRYS
FHRIISRYVLCQTDTKGGSGQAGGQSTFSLSL
FRAGMENT NO

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Dimerization:
HOMODIMER INFORMATION There is experimental evidence for homo-dimerization METHOD Bioluminescence Resonance Energy Transfer (BRET) REFERENCES 12804599

Coupling with G-proteins:
Family:Gs REFERENCES:11048721
1GPR0124Galpha-s-Rattus norvegicus-2
2GPR0392Galpha-s-Rattus norvegicus-1


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athina University of Athens
Faculty of Biology
Dept. of Cell Biology and Biophysics
Biophysics
& Bioinformatics
Laboratory