Details: |
NAME |
OPIOID AND OPIOID-LIKE RECEPTOR_MU OPIOID PEPTIDE (MOR)_Cavia porcellus |
DESCRIPTION |
Mu-type opioid receptor . |
SPECIES |
Cavia porcellus |
COMMON NAME |
Guinea pig |
NCBI Taxonomy |
10141 |
GENE |
OPRM1 |
SEQUENCE |
YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSI FTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI
|
FRAGMENT |
YES
|
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Homepage
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Dimerization: |
HOMODIMER INFORMATION |
There is experimental evidence for homo-dimerization
|
METHOD |
Bioluminescence Resonance Energy Transfer (BRET)
|
REFERENCES |
12217652
|
HOMODIMER INFORMATION |
There is experimental evidence for homo-dimerization
|
METHOD |
Immunoprecipitation
|
REFERENCES |
10842167
|
HETERODIMER INFORMATION |
Forms heterodimers with delta Opioid Peptide Receptor. Dimerization results in Changing the binding properties of opiate ligands and altered G-protein coupling
|
METHOD |
Immunoprecipitation
|
REFERENCES |
10842167 | 11069979
|
HETERODIMER INFORMATION |
Forms heterodimers with SST2 RECEPTORS. Dimerization results in cross-modulation of receptor phosphorylation, internalization and desensitization
|
METHOD |
Immunoprecipitation
|
REFERENCES |
11896051
|
Coupling with G-proteins: |
Family:Gi/o |
REFERENCES: | 8393525 | 1 | GPR0107 | Galpha-i3-Cavia porcellus | 2 | GPR0216 | Galpha-i1-Cavia porcellus | 3 | GPR0224 | Galpha-i2-Cavia porcellus |
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