gpDB: a database of GPCRs, G-proteins, Effectors and their interactions
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gpDB::GPCR View
Entry 1 of 1 :: GPCR1913 ::
CLASS CLASS A (RHODOPSIN LIKE)
FAMILY OPIOID AND OPIOID-LIKE RECEPTOR
SUBFAMILY N/OFQ RECEPTOR

Cross References:
UniProt P35370 | Q791R4 EMBL D16438 | U05239 | U01913 | L28144 | U07871 | L33916 | L29419 | AF216218 | AY152731
InterPro IPR000276 | IPR001418 | IPR001420 GPCRDB OPRX_RAT
GENEID 29256
PRINTS PR00237 | PR00384 | PR00547 PFAM PF00001

Details:
NAME OPIOID AND OPIOID-LIKE RECEPTOR_N/OFQ RECEPTOR_Rattus norvegicus-1
DESCRIPTION Nociceptin receptor (Orphanin FQ receptor) (Kappa-type 3 opioidreceptor) (KOR-3) (ROR-C) (XOR1).
SPECIES Rattus norvegicus COMMON NAME Rat NCBI Taxonomy 10116
GENE Oprl1 | Oor | Oprl
SEQUENCE
MESLFPAPYWEVLYGSHFQGNLSLLNETVPHHLLLNASHSAFLPLGLKVTIVGLYLAVCI
GGLLGNCLVMYVILRHTKMKTATNIYIFNLALADTLVLLTLPFQGTDILLGFWPFGNALC
KTVIAIDYYNMFTSTFTLTAMSVDRYVAICHPIRALDVRTSSKAQAVNVAIWALASVVGV
PVAIMGSAQVEDEEIECLVEIPAPQDYWGPVFAICIFLFSFIIPVLIISVCYSLMIRRLR
GVRLLSGSREKDRNLRRITRLVLVVVAVFVGCWTPVQVFVLVQGLGVQPGSETAVAILRF
CTALGYVNSCLNPILYAFLDENFKACFRKFCCASSLHREMQVSDRVRSIAKDVGLGCKTS
ETVPRPA
FRAGMENT NO

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Coupling with G-proteins:
Family:Gi/o REFERENCES:15019559
1GPR0026Galpha-o-Rattus norvegicus
2GPR0111Galpha-i3-Rattus norvegicus
3GPR0221Galpha-i1-Rattus norvegicus
4GPR0229Galpha-i2-Rattus norvegicus


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athina University of Athens
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Dept. of Cell Biology and Biophysics
Biophysics
& Bioinformatics
Laboratory