| Details: |
| NAME |
ADRENOCEPTOR (A1-ADRENOCEPTOR)_A1B(Adrenoceptor)_Mus musculus-1 |
| DESCRIPTION |
Alpha-1B adrenergic receptor (Alpha 1B-adrenoceptor) (Alpha 1B-adrenoreceptor). |
| SPECIES |
Mus musculus |
COMMON NAME |
Mouse |
NCBI Taxonomy |
10090 |
| GENE |
Adra1b |
| SEQUENCE |
MNPDLDTGHNTSAPAHWGELKDANFTGPNQTSSNSTLPQLDVTRAISVGCLGAFILFAIV
GNILVILSVACNRHLRTPTNYFIVNLAIADLLLSFTDLPFSATLEVLGYWVLGRIFCDIW
AAVDVLCCTASILSLCAISIDRYIGVRYSLQYPTLVTRRKAILALLSVWVLSTVISIGPL
LGWKEPAPNDDKECGVTEEPFYALFSSLGSFYIPLAVILVMYCRVYIVAKRTTKNLEAGV
MKEMSNSKELTLRIHSKNFHEDTLSSTKAKGHNPRSSIAVKLFKFSREKKAAKTLGIVVG
MFILCWLPFFIALPLGSLFSTLKPPDAVFKVVFWLGYFNSCLNPIIYPCSSKEFKRAFMR
ILGCQCRGGRRRRRRRRLGACAYTYRPWTRGGSLERSQSRKDSLDDSGSCMSGSQRTLPS
ASPSPGYLGRGTQPPVELCAFPEWKPGALLSLPEPPGRRGRLDSGPLFTFKLLGEPESPG
TEGDASNGGCDTTTDLANGQPGFKSNMPLAPGHF
|
FRAGMENT |
NO
|
|
|
|
|
Homepage
|
| Dimerization: |
| HOMODIMER INFORMATION |
There is experimental evidence for homo-dimerization
|
METHOD |
Immunoprecipitation, Fluorescence Resonance Energy Transfer (FRET)
|
REFERENCES |
12888550
|
| HETERODIMER INFORMATION |
Forms heterodimers with A1A Adrenoceptors. Heterodimerization results in altered internalization of the receptor
|
METHOD |
Fluorescence Resonance Energy Transfer (FRET)
|
REFERENCES |
12888550
|
| Scaffold: |
| TYPE |
nNOS( neuronal nitric oxide synthase) NOS1
|
REFERENCES |
12184796
|
| Coupling with G-proteins: |
| Family:Gq/11 |
REFERENCES: | 1662393 | | 1 | GPR0031 | Galpha-11-Mus musculus-2 | | 2 | GPR0240 | Galpha-q-Mus musculus | | 3 | GPR0360 | Galpha-11-Mus musculus-1 |
|
biol.uoa.gr
for comments, corrections and
data (sequence) submission.
