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gpDB::G-protein View
Entry 1 of 1 :: GPR0031 ::
CLASS Galpha
FAMILY Gq/11
SUBFAMILY Galpha-11
TYPE Galpha-11

Cross References:
UniProt P21278 | Q61939 EMBL M55411 | U37413 | U37411 | U37412 | M57617
InterPro IPR001019 | IPR000654 | IPR011025
PRODOM PD000281
GENEID 14672
PRINTS PR00318 | PR00442 PFAM PF00503

Details:
NAME Galpha-11-Mus musculus-2
DESCRIPTION Guanine nucleotide-binding protein alpha-11 subunit.
SPECIES Mus musculus COMMON NAME Mouse NCBI Taxonomy 10090
POST TRANSLATION MODIFICATIONS null GENE Gna11 | Gna-11
SEQUENCE 
MTLESMMACCLSDEVKESKRINAEIEKQLRRDKRDARRELKLLLLGTGESGKSTFIKQMR
IIHGAGYSEEDKRGFTKLVYQNIFTAMQAMVRAMETLKILYKYEQNKANALLIREVDVEK
VTTFEHQYVNAIKTLWSDPGVQECYDRRREFQLSDSAKYYLTDVDRIATVGYLPTQQDVL
RVRVPTTGIIEYPFDLENIIFRMVDVGGQRSERRKWIHCFENVTSIMFLVALSEYDQVLV
ESDNENRMEESKALFRTIITYPWFQNSSVILFLNKKDLLEDKILHSHLVDYFPEFDGPQR
DAQAAREFILKMFVDLNPDSDKIIYSHFTCATDTENIRFVFAAVKDTILQLNLKEYNLV
 FRAGMENT NO
FUNCTION Guanine nucleotide-binding proteins (G proteins) ares involved as modulators or transducers in various transmembranes signaling systems
Effectors:
1EFF0352GRK2-Mus musculus-1Inhibits PLC-beta activation and blocks Gqa-mediated GLUT4 translocation and glucose uptake in 3T3 adipocytes15251227 | 14654303 | 16182515
2EFF0353GRK2-Mus musculus-2Inhibits PLC-beta activation and blocks Gqa-mediated GLUT4 translocation and glucose uptake in 3T3 adipocytes15251227 | 14654303 | 16182515
3EFF0354GRK2-Mus musculus-3Inhibits PLC-beta activation and blocks Gqa-mediated GLUT4 translocation and glucose uptake in 3T3 adipocytes15251227 | 14654303 | 16182515
4EFF0355GRK2-Mus musculus-4Inhibits PLC-beta activation and blocks Gqa-mediated GLUT4 translocation and glucose uptake in 3T3 adipocytes15251227 | 14654303 | 16182515
5EFF0361GRK3-Mus musculus-1Stimulation15251227 | 14654303 | 16182515
6EFF0362GRK3-Mus musculus-2Stimulation15251227 | 14654303 | 16182515
7EFF0363GRK3-Mus musculus-3Stimulation15251227 | 14654303 | 16182515
8EFF0366GRK4-Mus musculusStimulation15251227 | 14654303
9EFF0523Phospholipase C beta-1-Mus musculus-1Stimulation of PLC-beta catalytic activity15251227 | 16182515 | 11015615
10EFF0524Phospholipase C beta-1-Mus musculus-2Stimulation of PLC-beta catalytic activity15251227 | 16182515 | 11015615
11EFF0525Phospholipase C beta-1-Mus musculus-3Stimulation of PLC-beta catalytic activity15251227 | 16182515 | 11015615
12EFF0526Phospholipase C beta-1-Mus musculus-4Stimulation of PLC-beta catalytic activity15251227 | 16182515 | 11015615
13EFF0527Phospholipase C beta-1-Mus musculus-5Stimulation of PLC-beta catalytic activity15251227 | 16182515 | 11015615
14EFF0532Phospholipase C beta-2-Mus musculus-1Stimulation of PLC-beta catalytic activity15251227 | 16182515 | 11015615
15EFF0533Phospholipase C beta-2-Mus musculus-2Stimulation of PLC-beta catalytic activity15251227 | 16182515 | 11015615
16EFF0535Phospholipase C beta-2-Mus musculus-3Stimulation of PLC-beta catalytic activity15251227 | 16182515 | 11015615
17EFF0537Phospholipase C beta-2-Mus musculus-4Stimulation of PLC-beta catalytic activity15251227 | 16182515 | 11015615
18EFF0543Phospholipase C beta-3-Mus musculus-1Stimulation of PLC-beta catalytic activity15251227 | 16182515 | 11015615
19EFF0544Phospholipase C beta-3-Mus musculus-2Stimulation of PLC-beta catalytic activity15251227 | 16182515 | 11015615
20EFF0545Phospholipase C beta-3-Mus musculus-3Stimulation of PLC-beta catalytic activity15251227 | 16182515 | 11015615
21EFF0546Phospholipase C beta-3-Mus musculus-4Stimulation of PLC-beta catalytic activity15251227 | 16182515 | 11015615
22EFF0547Phospholipase C beta-3-Mus musculus-5Stimulation of PLC-beta catalytic activity15251227 | 16182515 | 11015615
23EFF0548Phospholipase C beta-3-Mus musculus-6Stimulation of PLC-beta catalytic activity15251227 | 16182515 | 11015615
24EFF0549Phospholipase C beta-3-Mus musculus-7Stimulation of PLC-beta catalytic activity15251227 | 16182515 | 11015615
25EFF0550Phospholipase C beta-3-Mus musculus-8Stimulation of PLC-beta catalytic activity15251227 | 16182515 | 11015615
26EFF0551Phospholipase C beta-3-Mus musculus-9Stimulation of PLC-beta catalytic activity15251227 | 16182515 | 11015615
27EFF0564Phospholipase C beta-4-Mus musculus-1Stimulation of PLC-beta catalytic activity15251227 | 16182515 | 11015615
28EFF0565Phospholipase C beta-4-Mus musculus-2Stimulation of PLC-beta catalytic activity15251227 | 16182515 | 11015615
29EFF0566Phospholipase C beta-4-Mus musculus-3Stimulation of PLC-beta catalytic activity15251227 | 16182515 | 11015615
30EFF0567Phospholipase C beta-4-Mus musculus-4Stimulation of PLC-beta catalytic activity15251227 | 16182515 | 11015615
31EFF0568Phospholipase C beta-4-Mus musculus-5Stimulation of PLC-beta catalytic activity15251227 | 16182515 | 11015615

Coupling with GPCRs:
1GPCR00665-HYDROXYTRYPTAMINE RECEPTOR_5-HT-2A_Mus musculus1765383
2GPCR00835-HYDROXYTRYPTAMINE RECEPTOR_5-HT-2B_Mus musculus-18786115
3GPCR00855-HYDROXYTRYPTAMINE RECEPTOR_5-HT-2C_Mus musculus1302605
4GPCR0208ADRENOCEPTOR (A1-ADRENOCEPTOR)_A1A(Adrenoceptor)_Mus musculus8396931
5GPCR0220ADRENOCEPTOR (A1-ADRENOCEPTOR)_A1B(Adrenoceptor)_Mus musculus-11662393
6GPCR0221ADRENOCEPTOR (A1-ADRENOCEPTOR)_A1B(Adrenoceptor)_Mus musculus-21662393
7GPCR0229ADRENOCEPTOR (A1-ADRENOCEPTOR)_A1D(Adrenoceptor)_Mus musculus1656955
8GPCR0233ADRENOCEPTOR (A2-ADRENOCEPTOR)_A2A(Adrenoceptor)_Mus musculus8662784
9GPCR0409ANGIOTENSIN RECEPTOR_AT1_Mus musculus-28865167
10GPCR0421ANGIOTENSIN RECEPTOR_AT1_Mus musculus-18865167
11GPCR0461BRADYKININ RECEPTOR_B1_Mus musculus1657928
12GPCR0474BRADYKININ RECEPTOR_B2_Mus musculus1657928
13GPCR0448BOMBESIN RECEPTOR_BB1_Mus musculus8531502
14GPCR0452BOMBESIN RECEPTOR_BB2_Mus musculus8531502
15GPCR0455BOMBESIN RECEPTOR_BB3_Mus musculus8383682
16GPCR0993LEUKOTRIENE RECEPTOR_BLT_Mus musculus9177352
17GPCR2575CALCITONIN, AMYLIN, CGRP, AND ADRENOMEDULIN RECEPTOR_CALCITONIN_Mus musculus8732687
18GPCR2636EXTRACELLULAR CALCIUM-SENSING RECEPTOR_CASR_Mus musculus8255296
19GPCR0733CHOLECYSTOKININ AND GASTRIN RECEPTOR_CCK1_Mus musculus8503909
20GPCR0743CHOLECYSTOKININ AND GASTRIN RECEPTOR_CCK2_Mus musculus1280419
21GPCR2581CALCITONIN, AMYLIN, CGRP, AND ADRENOMEDULIN RECEPTOR_CGRP_Mus musculus2536720
22GPCR1000LEUKOTRIENE RECEPTOR_CYSLT-1_Mus musculus10391245
23GPCR1001LEUKOTRIENE RECEPTOR_CYSLT-2_Mus musculus10913337
24GPCR2420PROSTANOID RECEPTOR_EP1_Mus musculus8253813
25GPCR2430PROSTANOID RECEPTOR_EP3_Mus musculus11095474
26GPCR0815ENDOTHELIN RECEPTOR_ET-A_Mus musculus1849646
27GPCR0823ENDOTHELIN RECEPTOR_ET-B_Mus musculus1848367
28GPCR2439PROSTANOID RECEPTOR_FP_Mus musculus8300593
29GPCR2728FRIZZLED_Frizzled-1_Mus musculus11563835
30GPCR2739FRIZZLED_Frizzled-2_Mus musculus11563835
31GPCR0837GALANIN RECEPTOR_GAL2_Mus musculus9685625
32GPCR0905GONADOTROPIN-RELEASING HORMONE RECEPTOR_GNRH1_Mus musculus1333190
33GPCR2604GROWTH HORMONE RELEASING PEPTIDES RECEPTOR_Growth hormone secretagogue receptor type 1(Ghrelin receptor)_Mus musculus8688086
34GPCR0965HISTAMINE RECEPTOR_H1_Mus musculus1722337
35GPCR1009LYSOPHOSPHOLIPID RECEPTOR_LPA1_Mus musculus9600933
36GPCR1011LYSOPHOSPHOLIPID RECEPTOR_LPA2_Mus musculus9525886
37GPCR1016LYSOPHOSPHOLIPID RECEPTOR_LPA3_Mus musculus12215548
38GPCR0877GLYCOPROTEIN HORMONE RECEPTOR_LSH RECEPTOR_Mus musculus1516719
39GPCR0118ACETYLCHOLINE RECEPTOR (MUSCARINIC)_M1_Mus musculus3037705
40GPCR0136ACETYLCHOLINE RECEPTOR (MUSCARINIC)_M3_Mus musculus11242080
41GPCR0158ACETYLCHOLINE RECEPTOR (MUSCARINIC)_M5_Mus musculus3037705
42GPCR2796MELANIN-CONCENTRATING HORMONE RECEPTOR_MCHR1_Mus musculus10559938
43GPCR2647GLUTAMATE RECEPTOR (METABOTROPIC)_MGLU1_Mus musculus9076744
44GPCR1238NEUROMEDIN RECEPTOR_Neuromedin U 2_Mus musculus10894543
45GPCR2500TACHYKININ RECEPTOR_NK1_Mus musculus1370820
46GPCR2508TACHYKININ RECEPTOR_NK2_Mus musculus1370820
47GPCR2512TACHYKININ RECEPTOR_NK3_Mus musculus1370820
48GPCR1275NEUROTENSIN RECEPTOR_NTS1_Mus musculus8381365
49GPCR1277NEUROTENSIN RECEPTOR_NTS2_Mus musculus8647296
50GPCR2363OREXIN RECEPTOR_Orexin 1_Mus musculus9491897
51GPCR2368OREXIN RECEPTOR_Orexin 2_Mus musculus9491897
52GPCR2552VASOPRESSIN AND OXYTOCIN RECEPTOR_OT_Mus musculus1313946
53GPCR2373P2Y RECEPTOR_P2Y1_Mus musculus8159738
54GPCR2393P2Y RECEPTOR_P2Y2_Mus musculus8159738
55GPCR2401P2Y RECEPTOR_P2Y4_Mus musculus9396022
56GPCR2619VASOACTIVE INTESTINAL PEPTIDE AND PITUITARY ADENYLATE CYCLASE ACTIVATING PEPTIDE RECEPTOR_PAC1_Mus musculus8396727
57GPCR2453PROTEASE-ACTIVATED RECEPTOR_PAR1_Mus musculus10644723
58GPCR2459PROTEASE-ACTIVATED RECEPTOR_PAR2_Mus musculus15082510
59GPCR2462PROTEASE-ACTIVATED RECEPTOR_PAR3_Mus musculus15082510
60GPCR2466PROTEASE-ACTIVATED RECEPTOR_PAR4_Mus musculus15082510
61GPCR2413PLATELET ACTIVATING FACTOR (PAF) RECEPTOR_PLATELET ACTIVATING FACTOR (PAF) RECEPTOR_Mus musculus7876256
62GPCR1087LYSOPHOSPHOLIPID RECEPTOR_S1P2_Mus musculus10617617
63GPCR1096LYSOPHOSPHOLIPID RECEPTOR_S1P3_Mus musculus9409733
64GPCR1099LYSOPHOSPHOLIPID RECEPTOR_S1P4_Mus musculus10679247
65GPCR2452PROSTANOID RECEPTOR_TP_Mus musculus8300593
66GPCR2525THYROTROPIN-RELEASING HORMONE RECEPTOR_TRH1_Mus musculus2175902
67GPCR0897GLYCOPROTEIN HORMONE RECEPTOR_TSH RECEPTOR_Mus musculus-18552586
68GPCR2549UROTENSIN RECEPTOR_UROTENSIN II RECEPTOR_Mus musculus10499587
69GPCR2560VASOPRESSIN AND OXYTOCIN RECEPTOR_V1A_Mus musculus1560825
70GPCR2563VASOPRESSIN AND OXYTOCIN RECEPTOR_V1B_Mus musculus11091117
71GPCR1245NEUROPEPTIDE Y RECEPTOR_Y1_Mus musculus1321422



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