gpDB: a database of GPCRs, G-proteins, Effectors and their interactions
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gpDB::GPCR View
Entry 1 of 1 :: GPCR0225 ::
CLASS CLASS A (RHODOPSIN LIKE)
FAMILY ADRENOCEPTOR (A1-ADRENOCEPTOR)
SUBFAMILY A1D(Adrenoceptor)

Cross References:
UniProt P23944 | Q71UM4 EMBL M60654 | L31771 | AF071014
InterPro IPR000363 | IPR002233 | IPR000276 GPCRDB ADA1D_RAT
GENEID 29413
PRINTS PR01103 | PR00240 | PR00237 PFAM PF00001

Details:
NAME ADRENOCEPTOR (A1-ADRENOCEPTOR)_A1D(Adrenoceptor)_Rattus norvegicus
DESCRIPTION Alpha-1D adrenergic receptor (Alpha 1D-adrenoceptor) (Alpha 1D-adrenoreceptor) (Alpha-1A adrenergic receptor) (RA42).
SPECIES Rattus norvegicus COMMON NAME Rat NCBI Taxonomy 10116
GENE Adra1d | Adra1a
SEQUENCE
MTFRDILSVTFEGPRSSSSTGGSGAGGGAGTVGPEGGAVGGVPGATGGGAVVGTGSGEDN
QSSTGEPGAAASGEVNGSAAVGGLVVSAQGVGVGVFLAAFILTAVAGNLLVILSVACNRH
LQTVTNYFIVNLAVADLLLSAAVLPFSATMEVLGFWAFGRTFCDVWAAVDVLCCTASILS
LCTISVDRYVGVRHSLKYPAIMTERKAAAILALLWAVALVVSVGPLLGWKEPVPPDERFC
GITEEVGYAIFSSVCSFYLPMAVIVVMYCRVYVVARSTTRSLEAGIKREPGKASEVVLRI
HCRGAATSAKGYPGTQSSKGHTLRSSLSVRLLKFSREKKAAKTLAIVVGVFVLCWFPFFF
VLPLGSLFPQLKPSEGVFKVIFWLGYFNSCVNPLIYPCSSREFKRAFLRLLRCQCRRRRR
RLWAVYGHHWRASTGDARSDCAPSPRIAPPGAPLALTAHPGAGSADTPETQDSVSSSRKP
ASALREWRLLGPLQRPTTQLRAKVSSLSHKIRSGARRAETACALRSEVEAVSLNVPQDGA
EAVICQAYEPGDYSNLRETDI
FRAGMENT NO

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Scaffold:
TYPE nNOS( neuronal nitric oxide synthase) NOS1 REFERENCES 12184796

Coupling with G-proteins:
Family:Gq/11 REFERENCES:1656955
1GPR0032Galpha-11-Rattus norvegicus
2GPR0242Galpha-q-Rattus norvegicus


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athina University of Athens
Faculty of Biology
Dept. of Cell Biology and Biophysics
Biophysics
& Bioinformatics
Laboratory