gpDB: a database of GPCRs, G-proteins, Effectors and their interactions
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gpDB::GPCR View
Entry 1 of 1 :: GPCR2385 ::
CLASS CLASS A (RHODOPSIN LIKE)
FAMILY P2Y RECEPTOR
SUBFAMILY P2Y12

Cross References:
UniProt Q9EPX4 EMBL AF313450
InterPro IPR000276 | IPR002286 | IPR005394 GPCRDB P2Y12_RAT
GENEID 64803
PRINTS PR00237 | PR01569 | PR01157 PFAM PF00001

Details:
NAME P2Y RECEPTOR_P2Y12_Rattus norvegicus
DESCRIPTION P2Y purinoceptor 12 (P2Y12) (P2Y12 platelet ADP receptor).
SPECIES Rattus norvegicus COMMON NAME Rat NCBI Taxonomy 10116
GENE P2ry12 | P2y12
SEQUENCE
MEVPGANATSANTTSIPGTSTLCSRDYKITQVLFPLLYTVLFFAGLITNSLAMRIFFQIR
SKSNFIIFLKNTVISDLLMILTFPFKILSDAKLGAGHLRTLVCQVTSVTFYFTMYISISF
LGLITIDRYLKTTRPFKTSSPSNLLGAKILSVAIWAFMFLLSLPNMILTNRRPKDKDITK
CSFLKSEFGLVWHEIVNYICQVIFWINFLIVIVCYSLITKELYRSYVRTRGSAKAPKKRV
NIKVFIIIAVFFICFVPFHFARIPYTLSQTRAVFDCNAENTLFYVKESTLWLTSLNACLD
PFIYFFLCKSFRNSLMSMLRCSTSGANKKKGQEGGDPSEETPM
FRAGMENT NO

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Coupling with G-proteins:
Family:Gi/o REFERENCES:11196645
1GPR0026Galpha-o-Rattus norvegicus
2GPR0111Galpha-i3-Rattus norvegicus
3GPR0221Galpha-i1-Rattus norvegicus
4GPR0229Galpha-i2-Rattus norvegicus


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athina University of Athens
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Biophysics
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