gpDB: a database of GPCRs, G-proteins, Effectors and their interactions
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gpDB::GPCR View
Entry 1 of 1 :: GPCR2414 ::
CLASS CLASS A (RHODOPSIN LIKE)
FAMILY PROLACTIN RELEASING PEPTIDE RECEPTOR (PRRPR)
SUBFAMILY PrRP

Cross References:
UniProt Q64121 EMBL S77867
InterPro IPR000276 | IPR001402 GPCRDB PRLHR_RAT
GENEID 246075
PRINTS PR00237 | PR01018 PFAM PF00001

Details:
NAME PROLACTIN RELEASING PEPTIDE RECEPTOR (PRRPR)_PrRP_Rattus norvegicus
DESCRIPTION Prolactin-releasing peptide receptor (PrRP receptor) (PrRPR) (G-protein coupled receptor 10) (UHR-1).
SPECIES Rattus norvegicus COMMON NAME Rat NCBI Taxonomy 10116
GENE Prlhr | Gpr10
SEQUENCE
MTSLPPGTTGDPDLFSGPSPAGSTPANQSAEASESNVSATVPRAAAVTPFQSLQLVHQLK
GLIVMLYSIVVVVGLVGNCLLVLVIARVRRLHNVTNFLIGNLALSDVLMCAACVPLTLAY
AFEPRGWVFGGGLCHLVFFLQPVTVYVSVFTLTTIAVDRYVVLVHPLRRRISLKLSAYAV
LGIWALSAVLALPAAVHTYHVELKPHDVRLCEEFWGSQERQRQIYAWGLLLGTYLLPLLA
ILLSYVRVSVKLRNRVVPGSVTQSQADWDRARRRRTFCLLVVVVVVFALCWLPLHIFNLL
RDLDPRAIDPYAFGLVQLLCHWLAMSSACYNPFIYAWLHDSFREELRKMLLSWPRKIVPH
GQNMTVSVVI
FRAGMENT NO

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Scaffold:
TYPE GRIP1( glutamate receptor interacting protein 1) REFERENCES 11641419
TYPE GRIP2 ( ABP) ( glutamate receptor interacting protein 2) REFERENCES 11641419
TYPE PICK1( protein interacting with protein kinase) REFERENCES
TYPE Shank3/ProSAP2( proline-rich synapse-associated protein 2) REFERENCES 11641419

Coupling with G-proteins:
Family:Gq/11 REFERENCES:11030716
1GPR0032Galpha-11-Rattus norvegicus
2GPR0242Galpha-q-Rattus norvegicus


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athina University of Athens
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Biophysics
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Laboratory