gpDB: a database of GPCRs, G-proteins, Effectors and their interactions
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gpDB::GPCR View
Entry 1 of 1 :: GPCR2436 ::
CLASS CLASS A (RHODOPSIN LIKE)
FAMILY PROSTANOID RECEPTOR
SUBFAMILY EP4

Cross References:
UniProt P35408 | Q3MJ87 EMBL L28175 | L25124 | X97873 | X97874 | D28472 | AY429109 | DQ400918 | BC101534 | BC113523
InterPro IPR000276 | IPR001758 | IPR008365 | IPR001244 GPCRDB PE2R4_HUMAN
GENEID 5734 MIM 601586
PRINTS PR00237 | PR00428 | PR01788 | PR00586 PFAM PF00001

Details:
NAME PROSTANOID RECEPTOR_EP4_Homo sapiens
DESCRIPTION Prostaglandin E2 receptor EP4 subtype (Prostanoid EP4 receptor) (PGEreceptor, EP4 subtype).
SPECIES Homo sapiens COMMON NAME Human NCBI Taxonomy 9606
GENE PTGER4 | PTGER2
SEQUENCE 
MSTPGVNSSASLSPDRLNSPVTIPAVMFIFGVVGNLVAIVVLCKSRKEQKETTFYTLVCG
LAVTDLLGTLLVSPVTIATYMKGQWPGGQPLCEYSTFILLFFSLSGLSIICAMSVERYLA
INHAYFYSHYVDKRLAGLTLFAVYASNVLFCALPNMGLGSSRLQYPDTWCFIDWTTNVTA
HAAYSYMYAGFSSFLILATVLCNVLVCGALLRMHRQFMRRTSLGTEQHHAAAAASVASRG
HPAASPALPRLSDFRRRRSFRRIAGAEIQMVILLIATSLVVLICSIPLVVRVFVNQLYQP
SLEREVSKNPDLQAIRIASVNPILDPWIYILLRKTVLSKAIEKIKCLFCRIGGSRRERSG
QHCSDSQRTSSAMSGHSRSFISRELKEISSTSQTLLPDLSLPDLSENGLGGRNLLPGVPG
MGLAQEDTTSLRTLRISETSDSSQGQDSESVLLVDEAGGSGRAGPAPKGSSLQVTFPSET
LNLSEKCI
 FRAGMENT NO

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Coupling with G-proteins:
Family:Gs REFERENCES:8016385
1GPR0119Galpha-s-Homo sapiens-2
2GPR0263Galpha-s-Homo sapiens-4
3GPR0266Galpha-s-Homo sapiens-5
4GPR0267Galpha-s-Homo sapiens-6
5GPR0277Galpha-s-Homo sapiens-7
6GPR0278Galpha-s-Homo sapiens
7GPR0395Galpha-s-Homo sapiens-3

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athina University of Athens
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 Dept. of Cell Biology and Biophysics
Biophysics
& Bioinformatics
Laboratory