gpDB: a database of GPCRs, G-proteins, Effectors and their interactions
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gpDB::GPCR View
Entry 1 of 1 :: GPCR2447 ::
CLASS CLASS A (RHODOPSIN LIKE)
FAMILY PROSTANOID RECEPTOR
SUBFAMILY IP

Cross References:
UniProt P43119 EMBL L29016 | D25418 | D29634 | D38127 | AY242134 | BC075814
InterPro IPR000276 | IPR008365 | IPR000370 | IPR001105 GPCRDB PI2R_HUMAN
GENEID 5739 MIM 600022
PRINTS PR00237 | PR01788 | PR00856 | PR00429 PFAM PF00001

Details:
NAME PROSTANOID RECEPTOR_IP_Homo sapiens
DESCRIPTION Prostacyclin receptor (Prostanoid IP receptor) (PGI receptor)(Prostaglandin I2 receptor).
SPECIES Homo sapiens COMMON NAME Human NCBI Taxonomy 9606
GENE PTGIR | PRIPR
SEQUENCE
MADSCRNLTYVRGSVGPATSTLMFVAGVVGNGLALGILSARRPARPSAFAVLVTGLAATD
LLGTSFLSPAVFVAYARNSSLLGLARGGPALCDAFAFAMTFFGLASMLILFAMAVERCLA
LSHPYLYAQLDGPRCARLALPAIYAFCVLFCALPLLGLGQHQQYCPGSWCFLRMRWAQPG
GAAFSLAYAGLVALLVAAIFLCNGSVTLSLCRMYRQQKRHQGSLGPRPRTGEDEVDHLIL
LALMTVVMAVCSLPLTIRCFTQAVAPDSSSEMGDLLAFRFYAFNPILDPWVFILFRKAVF
QRLKLWVCCLCLGPAHGDSQTPLSQLASGRRDPRAPSAPVGKEGSCVPLSAWGEGQVEPL
PPTQQSSGSAVGTSSKAEASVACSLC
FRAGMENT NO

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Coupling with G-proteins:
Family:Gs REFERENCES:7512962
1GPR0119Galpha-s-Homo sapiens-2
2GPR0263Galpha-s-Homo sapiens-4
3GPR0266Galpha-s-Homo sapiens-5
4GPR0267Galpha-s-Homo sapiens-6
5GPR0277Galpha-s-Homo sapiens-7
6GPR0278Galpha-s-Homo sapiens
7GPR0395Galpha-s-Homo sapiens-3


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Biophysics
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Laboratory