gpDB: a database of GPCRs, G-proteins, Effectors and their interactions
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gpDB::GPCR View
Entry 1 of 1 :: GPCR2449 ::
CLASS CLASS A (RHODOPSIN LIKE)
FAMILY PROSTANOID RECEPTOR
SUBFAMILY TP

Cross References:
UniProt P21731 | Q6DK52 EMBL D38081 | U11271 | U27325 | D15056 | AY429110 | DQ268653 | AC005175 | BC074749 | BC074750
InterPro IPR000276 | IPR008365 | IPR001105 PDB 1LBN GPCRDB TA2R_HUMAN
MIM 188070
PRINTS PR00237 | PR01788 | PR00429 PFAM PF00001

Details:
NAME PROSTANOID RECEPTOR_TP_Homo sapiens
DESCRIPTION Thromboxane A2 receptor (TXA2-R) (Prostanoid TP receptor).
SPECIES Homo sapiens COMMON NAME Human NCBI Taxonomy 9606
GENE TBXA2R
SEQUENCE
MWPNGSSLGPCFRPTNITLEERRLIASPWFAASFCVVGLASNLLALSVLAGARQGGSHTR
SSFLTFLCGLVLTDFLGLLVTGTIVVSQHAALFEWHAVDPGCRLCRFMGVVMIFFGLSPL
LLGAAMASERYLGITRPFSRPAVASQRRAWATVGLVWAAALALGLLPLLGVGRYTVQYPG
SWCFLTLGAESGDVAFGLLFSMLGGLSVGLSFLLNTVSVATLCHVYHGQEAAQQRPRDSE
VEMMAQLLGIMVVASVCWLPLLVFIAQTVLRNPPAMSPAGQLSRTTEKELLIYLRVATWN
QILDPWVYILFRRAVLRRLQPRLSTRPRRVSLCGPAWSTVARSRLTATSASRVQAILVPQ
PPEQLGLQA
FRAGMENT NO

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Coupling with G-proteins:
Family:G12/13 REFERENCES:10318854
1GPR0034Galpha-12-Homo sapiens
2GPR0037Galpha-13-Homo sapiens
Family:Gq/11 REFERENCES:8300593
3GPR0002Galpha-q-Homo sapiens-2
4GPR0029Galpha-11-Homo sapiens
5GPR0237Galpha-q-Homo sapiens-1


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athina University of Athens
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Dept. of Cell Biology and Biophysics
Biophysics
& Bioinformatics
Laboratory