gpDB: a database of GPCRs, G-proteins, Effectors and their interactions
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gpDB::GPCR View
Entry 1 of 1 :: GPCR2504 ::
CLASS CLASS A (RHODOPSIN LIKE)
FAMILY TACHYKININ RECEPTOR
SUBFAMILY NK2

Cross References:
UniProt P21452 | Q9UDE7 EMBL M57414 | M60284 | M57415 | M60281 | M60282 | M60283 | M75105 | M75101 | M75102 | M75103 | M75104 | AY322545
InterPro IPR000276 | IPR001681 | IPR000913 GPCRDB NK2R_HUMAN
GENEID 6865 MIM 162321
PRINTS PR00237 | PR01025 | PR00244 PFAM PF00001

Details:
NAME TACHYKININ RECEPTOR_NK2_Homo sapiens-1
DESCRIPTION Substance-K receptor (SKR) (Neurokinin A receptor) (NK-2 receptor)(NK-2R) (Tachykinin receptor 2).
SPECIES Homo sapiens COMMON NAME Human NCBI Taxonomy 9606
GENE TACR2 | NK2R | NKNAR | TAC2R
SEQUENCE 
MGTCDIVTEANISSGPESNTTGITAFSMPSWQLALWATAYLALVLVAVTGNAIVIWIILA
HRRMRTVTNYFIVNLALADLCMAAFNAAFNFVYASHNIWYFGRAFCYFQNLFPITAMFVS
IYSMTAIAADRYMAIVHPFQPRLSAPSTKAVIAGIWLVALALASPQCFYSTVTMDQGATK
CVVAWPEDSGGKTLLLYHLVVIALIYFLPLAVMFVAYSVIGLTLWRRAVPGHQAHGANLR
HLQAKKKFVKTMVLVVLTFAICWLPYHLYFILGSFQEDIYCHKFIQQVYLALFWLAMSST
MYNPIIYCCLNHRFRSGFRLAFRCCPWVTPTKEDKLELTPTTSLSTRVNRCHTKETLFMA
GDTAPSEATSGEAGRPQDGSGLWFGYGLLAPTKTHVEI
 FRAGMENT NO

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Coupling with G-proteins:
Family:Gq/11 REFERENCES:1370820
1GPR0002Galpha-q-Homo sapiens-2
2GPR0029Galpha-11-Homo sapiens
3GPR0237Galpha-q-Homo sapiens-1
Family:Gs REFERENCES:1370820
4GPR0119Galpha-s-Homo sapiens-2
5GPR0263Galpha-s-Homo sapiens-4
6GPR0266Galpha-s-Homo sapiens-5
7GPR0267Galpha-s-Homo sapiens-6
8GPR0277Galpha-s-Homo sapiens-7
9GPR0278Galpha-s-Homo sapiens
10GPR0395Galpha-s-Homo sapiens-3

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athina University of Athens
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 Dept. of Cell Biology and Biophysics
Biophysics
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Laboratory