gpDB: a database of GPCRs, G-proteins, Effectors and their interactions
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gpDB::GPCR View
Entry 1 of 1 :: GPCR0257 ::
CLASS CLASS A (RHODOPSIN LIKE)
FAMILY ADRENOCEPTOR (A2-ADRENOCEPTOR)
SUBFAMILY A2B(Adrenoceptor)

Cross References:
UniProt O77700 EMBL Y15944
InterPro IPR015695 | IPR000207 | IPR002233 | IPR000276 GPCRDB ADA2B_BOVIN
PRINTS PR01103 | PR00559 | PR00237 PFAM PF00001

Details:
NAME ADRENOCEPTOR (A2-ADRENOCEPTOR)_A2B(Adrenoceptor)_Bos taurus
DESCRIPTION Alpha-2B adrenergic receptor .
SPECIES Bos taurus COMMON NAME Bovine NCBI Taxonomy 9913
GENE ADRA2B
SEQUENCE 
AIAAVITFLILFTIFGNALVILAVLTSRSLRAPQNLFLVSLAAADILVATLIIPFSLANE
LLGYWYFWRTWCEVYLALDVLFCTSSIVHLCAISLDRYWAVSRALEYNSKRTPRRIKFII
LIVWLIAAVISLPPLIYKGDQGPQPLARPQCKLNQEAWYILASSIGSFFAPCLIMILVYL
RIYLIAKRSHCRGPRAKGGPGERESKQPHPVPGEVSDSAKLPTLASQLATPGEANGCSQP
RPGEKGDGETPEAPGTPALPPSWPAIPKSGQGQKEGVCGSSPEEEAEEEEEEGCEPQALP
ASPASACSPPLQQPQGSRVLATLRGQVLLGRGTGTAGAQWWRRRTQLSREKRFTFVLAVV
IGVFVLCWFPFFFSYSLGAICPQHCKVPHGLF
 FRAGMENT YES

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Scaffold:
TYPE 15-3-3 ksi REFERENCES 10224112
TYPE GASP( GPCR associated sorting protein) REFERENCES 12142540
TYPE Spinophilin/neurabin II REFERENCES 11154706

Coupling with G-proteins:
Family:Gi/o REFERENCES:2164221
1GPR0017Galpha-o1-Bos taurus
2GPR0219Galpha-i1-Bos taurus
3GPR0294Galpha-i2-Bos taurus-2
4GPR0295Galpha-i2-Bos taurus-1

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