gpDB: a database of GPCRs, G-proteins, Effectors and their interactions
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gpDB::GPCR View
Entry 1 of 1 :: GPCR2580 ::
CLASS CLASS B (SECRETIN LIKE)
FAMILY CALCITONIN, AMYLIN, CGRP, AND ADRENOMEDULIN RECEPTOR
SUBFAMILY CGRP

Cross References:
UniProt Q16602 EMBL L76380 | U17473 | AY389506
InterPro IPR003287 | IPR003289 | IPR001879 | IPR000832 GPCRDB CALRL_HUMAN
GENEID 10203 MIM 114190
PRINTS PR01351 | PR01350 | PR00249 PFAM PF00002 | PF02793

Details:
NAME CALCITONIN, AMYLIN, CGRP, AND ADRENOMEDULIN RECEPTOR_CGRP_Homo sapiens
DESCRIPTION Calcitonin gene-related peptide type 1 receptor precursor (CGRP type 1receptor) (Calcitonin receptor-like receptor).
SPECIES Homo sapiens COMMON NAME Human NCBI Taxonomy 9606
GENE CALCRL | CGRPR
SEQUENCE 
MEKKCTLYFLVLLPFFMILVTAELEESPEDSIQLGVTRNKIMTAQYECYQKIMQDPIQQA
EGVYCNRTWDGWLCWNDVAAGTESMQLCPDYFQDFDPSEKVTKICDQDGNWFRHPASNRT
WTNYTQCNVNTHEKVKTALNLFYLTIIGHGLSIASLLISLGIFFYFKSLSCQRITLHKNL
FFSFVCNSVVTIIHLTAVANNQALVATNPVSCKVSQFIHLYLMGCNYFWMLCEGIYLHTL
IVVAVFAEKQHLMWYYFLGWGFPLIPACIHAIARSLYYNDNCWISSDTHLLYIIHGPICA
ALLVNLFFLLNIVRVLITKLKVTHQAESNLYMKAVRATLILVPLLGIEFVLIPWRPEGKI
AEEVYDYIMHILMHFQGLLVSTIFCFFNGEVQAILRRNWNQYKIQFGNSFSNSEALRSAS
YTVSTISDGPGYSHDCPSEHLNGKSIHDIENVLLKPENLYN
 FRAGMENT NO

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Coupling with G-proteins:
Family:Gq/11 REFERENCES:2536720
1GPR0002Galpha-q-Homo sapiens-2
2GPR0029Galpha-11-Homo sapiens
3GPR0237Galpha-q-Homo sapiens-1
Family:Gs REFERENCES:2542467
4GPR0119Galpha-s-Homo sapiens-2
5GPR0263Galpha-s-Homo sapiens-4
6GPR0266Galpha-s-Homo sapiens-5
7GPR0267Galpha-s-Homo sapiens-6
8GPR0277Galpha-s-Homo sapiens-7
9GPR0278Galpha-s-Homo sapiens
10GPR0395Galpha-s-Homo sapiens-3

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athina University of Athens
 Faculty of Biology
 Dept. of Cell Biology and Biophysics
Biophysics
& Bioinformatics
Laboratory