gpDB: a database of GPCRs, G-proteins, Effectors and their interactions
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gpDB::GPCR View
Entry 1 of 1 :: GPCR2588 ::
CLASS CLASS B (SECRETIN LIKE)
FAMILY CORTICOTROPIN-RELEASING FACTOR RECEPTOR
SUBFAMILY CRF1

Cross References:
UniProt P35353 EMBL L24096 | L25438 | U53498 | U53486 | U53487 | U53488 | U53489 | U53490 | U53491 | U53492 | U53493 | U53494 | U53495 | U53496 | U53497
InterPro IPR003052 | IPR003051 | IPR001879 | IPR000832 GPCRDB CRFR1_RAT
GENEID 58959
PRINTS PR01279 | PR01280 | PR00249 PFAM PF00002 | PF02793

Details:
NAME CORTICOTROPIN-RELEASING FACTOR RECEPTOR_CRF1_Rattus norvegicus
DESCRIPTION Corticotropin-releasing factor receptor 1 precursor (CRF-R) (CRF1)(Corticotropin-releasing hormone receptor 1) (CRH-R 1).
SPECIES Rattus norvegicus COMMON NAME Rat NCBI Taxonomy 10116
GENE Crhr1 | Crhr
SEQUENCE
MGRRPQLRLVKALLLLGLNPVSTSLQDQRCENLSLTSNVSGLQCNASVDLIGTCWPRSPA
GQLVVRPCPAFFYGVRYNTTNNGYRECLANGSWAARVNYSECQEILNEEKKSKVHYHVAV
IINYLGHCISLVALLVAFVLFLRLRSIRCLRNIIHWNLISAFILRNATWFVVQLTVSPEV
HQSNVAWCRLVTAAYNYFHVTNFFWMFGEGCYLHTAIVLTYSTDRLRKWMFVCIGWGVPF
PIIVAWAIGKLHYDNEKCWFGKRPGVYTDYIYQGPMILVLLINFIFLFNIVRILMTKLRA
STTSETIQYRKAVKATLVLLPLLGITYMLFFVNPGEDEVSRVVFIYFNSFLESFQGFFVS
VFYCFLNSEVRSAIRKRWRRWQDKHSIRARVARAMSIPTSPTRVSFHSIKQSTAV
FRAGMENT NO

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Coupling with G-proteins:
Family:Gs REFERENCES:1280419
1GPR0124Galpha-s-Rattus norvegicus-2
2GPR0392Galpha-s-Rattus norvegicus-1


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athina University of Athens
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Dept. of Cell Biology and Biophysics
Biophysics
& Bioinformatics
Laboratory