gpDB: a database of GPCRs, G-proteins, Effectors and their interactions
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gpDB::GPCR View
Entry 1 of 1 :: GPCR2589 ::
CLASS CLASS B (SECRETIN LIKE)
FAMILY CORTICOTROPIN-RELEASING FACTOR RECEPTOR
SUBFAMILY CRF2

Cross References:
UniProt Q60748 | Q60783 | Q60808 EMBL U17858 | U21729 | U19939
InterPro IPR003053 | IPR003051 | IPR001879 | IPR000832 PDB 1U34 | 2JNC | 2JND GPCRDB CRFR2_MOUSE
GENEID 12922
PRINTS PR01279 | PR01281 | PR00249 PFAM PF00002 | PF02793

Details:
NAME CORTICOTROPIN-RELEASING FACTOR RECEPTOR_CRF2_Mus musculus
DESCRIPTION Corticotropin-releasing factor receptor 2 precursor (CRF-R 2) (CRF2)(Corticotropin-releasing hormone receptor 2) (CRH-R 2) (CRF-RB) (CRH-R2).
SPECIES Mus musculus COMMON NAME Mouse NCBI Taxonomy 10090
GENE Crhr2 | Crf2r
SEQUENCE
MGTPGSLPSAQLLLCLFSLLPVLQVAQPGQAPQDQPLWTLLEQYCHRTTIGNFSGPYTYC
NTTLDQIGTCWPQSAPGALVERPCPEYFNGIKYNTTRNAYRECLENGTWASRVNYSHCEP
ILDDKQRKYDLHYRIALIVNYLGHCVSVVALVAAFLLFLVLRSIRCLRNVIHWNLITTFI
LRNIAWFLLQLIDHEVHEGNEVWCRCITTIFNYFVVTNFFWMFVEGCYLHTAIVMTYSTE
HLRKWLFLFIGWCIPCPIIIAWAVGKLYYENEQCWFGKEAGDLVDYIYQGPVMLVLLINF
VFLFNIVRILMTKLRASTTSETIQYRKAVKATLVLLPLLGITYMLFFVNPGEDDLSQIVF
IYFNSFLQSFQGFFVSVFYCFFNGEVRAALRKRWHRWQDHHALRVPVARAMSIPTSPTRI
SFHSIKQTAAV
FRAGMENT NO

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Coupling with G-proteins:
Family:Gs REFERENCES:8536644
1GPR0123Galpha-s-Mus musculus-2
2GPR0391Galpha-s-Mus musculus


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athina University of Athens
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Dept. of Cell Biology and Biophysics
Biophysics
& Bioinformatics
Laboratory