gpDB::G-protein View

CLASS	Galpha
FAMILY	Gs
SUBFAMILY	Galpha-s
TYPE	Galpha-s

Cross References:
UniProt	P63094 \| A2A611 \| A2A612 \| A2A613 \| P04894 \| P08755 \| Q3KQM5 \| Q3TFV3	EMBL	Y00703 \| M13964 \| AF107848 \| AK147051 \| AK159563 \| AK168996 \| AL593857 \| AL593857 \| AL593857 \| BC038067 \| BC048834 \| BC061496 \| BC062654 \| BC080816 \| BC092055 \| BC106133 \| AB041808
InterPro	IPR001019 \| IPR000367 \| IPR011025
PRODOM	PD000281
GENEID	14683
PRINTS	PR00318 \| PR00443	PFAM	PF00503

Details:
NAME	Galpha-s-Mus musculus-2
DESCRIPTION	Guanine nucleotide-binding protein G(s) subunit alpha isoforms short(Adenylate cyclase-stimulating G alpha protein).
SPECIES	Mus musculus	COMMON NAME	Mouse	NCBI Taxonomy	10090
POST TRANSLATION MODIFICATIONS	null	GENE	Gnas \| Gnas1 \| MNCb-5546
SEQUENCE	MGCLGNSKTEDQRNEEKAQREANKKIEKQLQKDKQVYRATHRLLLLGAGESGKSTIVKQM RILHVNGFNGEGGEEDPQAARSNSDGEKATKVQDIKNNLKEAIETIVAAMSNLVPPVELA NPENQFRVDYILSVMNVPNFDFPPEFYEHAKALWEDEGVRACYERSNEYQLIDCAQYFLD KIDVIKQADYVPSDQDLLRCRVLTSGIFETKFQVDKVNFHMFDVGGQRDERRKWIQCFND VTAIIFVVASSSYNMVIREDNQTNRLQEALNLFKSIWNNRWLRTISVILFLNKQDLLAEK VLAGKSKIEDYFPEFARYTTPEDATPEPGEDPRVTRAKYFIRDEFLRISTASGDGRHYCY PHFTCAVDTENIRRVFNDCRDIIQRMHLRQYELL				FRAGMENT	NO
FUNCTION	Guanine nucleotide-binding proteins (G proteins) ares involved as modulators or transducers in various transmembranes signaling systems

Effectors:
1	EFF0004	Adenylate cyclase-1-Mus musculus-1	Stimulation	15251227 \| 15922020 \| 14993377 \| 11376933
2	EFF0005	Adenylate cyclase-1-Mus musculus-2	Stimulation	15251227 \| 15922020 \| 14993377 \| 11376933
3	EFF0009	Adenylate cyclase-2-Mus musculus-1	Stimulation	15251227 \| 15922020 \| 14993377 \| 11376933
4	EFF0010	Adenylate cyclase-2-Mus musculus-2	Stimulation	15251227 \| 15922020 \| 14993377 \| 11376933
5	EFF0014	Adenylate cyclase-3-Mus musculus-1	Stimulation	15251227 \| 15922020 \| 14993377 \| 11376933
6	EFF0015	Adenylate cyclase-3-Mus musculus-2	Stimulation	15251227 \| 15922020 \| 14993377 \| 11376933
7	EFF0016	Adenylate cyclase-3-Mus musculus-3	Stimulation	15251227 \| 15922020 \| 14993377 \| 11376933
8	EFF0017	Adenylate cyclase-3-Mus musculus-4	Stimulation	15251227 \| 15922020 \| 14993377 \| 11376933
9	EFF0018	Adenylate cyclase-3-Mus musculus-5	Stimulation	15251227 \| 15922020 \| 14993377 \| 11376933
10	EFF0022	Adenylate cyclase-4-Mus musculus-1	Stimulation	15251227 \| 15922020 \| 14993377 \| 11376933
11	EFF0023	Adenylate cyclase-4-Mus musculus-2	Stimulation	15251227 \| 15922020 \| 14993377 \| 11376933
12	EFF0024	Adenylate cyclase-4-Mus musculus-3	Stimulation	15251227 \| 15922020 \| 14993377 \| 11376933
13	EFF0025	Adenylate cyclase-4-Mus musculus-4	Stimulation	15251227 \| 15922020 \| 14993377 \| 11376933
14	EFF0032	Adenylate cyclase-5-Mus musculus-1	Stimulation	15251227 \| 15922020 \| 14993377 \| 11376933
15	EFF0033	Adenylate cyclase-5-Mus musculus-2	Stimulation	15251227 \| 15922020 \| 14993377 \| 11376933
16	EFF0040	Adenylate cyclase-6-Mus musculus-1	Stimulation	15251227 \| 15922020 \| 14993377 \| 11376933
17	EFF0041	Adenylate cyclase-6-Mus musculus-2	Stimulation	15251227 \| 15922020 \| 14993377 \| 11376933
18	EFF0046	Adenylate cyclase-7-Mus musculus-1	Stimulation	15251227 \| 15922020 \| 14993377 \| 11376933
19	EFF0047	Adenylate cyclase-7-Mus musculus-2	Stimulation	15251227 \| 15922020 \| 14993377 \| 11376933
20	EFF0048	Adenylate cyclase-7-Mus musculus-3	Stimulation	15251227 \| 15922020 \| 14993377 \| 11376933
21	EFF0049	Adenylate cyclase-7-Mus musculus-4	Stimulation	15251227 \| 15922020 \| 14993377 \| 11376933
22	EFF0050	Adenylate cyclase-7-Mus musculus-5	Stimulation	15251227 \| 15922020 \| 14993377 \| 11376933
23	EFF0051	Adenylate cyclase-7-Mus musculus-6	Stimulation	15251227 \| 15922020 \| 14993377 \| 11376933
24	EFF0057	Adenylate cyclase-8-Mus musculus-1	Stimulation	15251227 \| 15922020 \| 14993377 \| 11376933
25	EFF0058	Adenylate cyclase-8-Mus musculus-2	Stimulation	15251227 \| 15922020 \| 14993377 \| 11376933
26	EFF0063	Adenylate cyclase-9-Mus musculus-1	Stimulation	15251227 \| 15922020 \| 14993377 \| 11376933
27	EFF0064	Adenylate cyclase-9-Mus musculus-2	Stimulation	15251227 \| 15922020 \| 14993377 \| 11376933
28	EFF0859	Src tyrosine kinase-Mus musculus-1	Stimulation	11007482 \| 15251227 \| 12209124
29	EFF0860	Src tyrosine kinase-Mus musculus-2	Stimulation	11007482 \| 15251227 \| 12209124
30	EFF0861	Src tyrosine kinase-Mus musculus-3	Stimulation	11007482 \| 15251227 \| 12209124
31	EFF0862	Src tyrosine kinase-Mus musculus-4	Stimulation	11007482 \| 15251227 \| 12209124
32	EFF0863	Src tyrosine kinase-Mus musculus-5	Stimulation	11007482 \| 15251227 \| 12209124
33	EFF0864	Src tyrosine kinase-Mus musculus-6	Stimulation	11007482 \| 15251227 \| 12209124
34	EFF0865	Src tyrosine kinase-Mus musculus-7	Stimulation	11007482 \| 15251227 \| 12209124
35	EFF0866	Src tyrosine kinase-Mus musculus-8	Stimulation	11007482 \| 15251227 \| 12209124
36	EFF1192	Tubulin-Mus musculus-1	Stimulation of GTPase activity	10224115 \| 15251227 \| 16380086
37	EFF1193	Tubulin-Mus musculus-10	Stimulation of GTPase activity	10224115 \| 15251227 \| 16380086
38	EFF1194	Tubulin-Mus musculus-11	Stimulation of GTPase activity	10224115 \| 15251227 \| 16380086
39	EFF1195	Tubulin-Mus musculus-12	Stimulation of GTPase activity	10224115 \| 15251227 \| 16380086
40	EFF1202	Tubulin-Mus musculus-19	Stimulation of GTPase activity	10224115 \| 15251227 \| 16380086
41	EFF1203	Tubulin-Mus musculus-2	Stimulation of GTPase activity	10224115 \| 15251227 \| 16380086
42	EFF1209	Tubulin-Mus musculus-25	Stimulation of GTPase activity	10224115 \| 15251227 \| 16380086
43	EFF1214	Tubulin-Mus musculus-3	Stimulation of GTPase activity	10224115 \| 15251227 \| 16380086
44	EFF1217	Tubulin-Mus musculus-32	Stimulation of GTPase activity	10224115 \| 15251227 \| 16380086
45	EFF1218	Tubulin-Mus musculus-33	Stimulation of GTPase activity	10224115 \| 15251227 \| 16380086
46	EFF1220	Tubulin-Mus musculus-35	Stimulation of GTPase activity	10224115 \| 15251227 \| 16380086
47	EFF1221	Tubulin-Mus musculus-34	Stimulation of GTPase activity	10224115 \| 15251227 \| 16380086
48	EFF1223	Tubulin-Mus musculus-31	Stimulation of GTPase activity	10224115 \| 15251227 \| 16380086
49	EFF1225	Tubulin-Mus musculus-4	Stimulation of GTPase activity	10224115 \| 15251227 \| 16380086
50	EFF1226	Tubulin-Mus musculus-30	Stimulation of GTPase activity	10224115 \| 15251227 \| 16380086
51	EFF1227	Tubulin-Mus musculus-29	Stimulation of GTPase activity	10224115 \| 15251227 \| 16380086
52	EFF1228	Tubulin-Mus musculus-28	Stimulation of GTPase activity	10224115 \| 15251227 \| 16380086
53	EFF1230	Tubulin-Mus musculus-27	Stimulation of GTPase activity	10224115 \| 15251227 \| 16380086
54	EFF1231	Tubulin-Mus musculus-26	Stimulation of GTPase activity	10224115 \| 15251227 \| 16380086
55	EFF1232	Tubulin-Mus musculus-24	Stimulation of GTPase activity	10224115 \| 15251227 \| 16380086
56	EFF1233	Tubulin-Mus musculus-23	Stimulation of GTPase activity	10224115 \| 15251227 \| 16380086
57	EFF1235	Tubulin-Mus musculus-22	Stimulation of GTPase activity	10224115 \| 15251227 \| 16380086
58	EFF1236	Tubulin-Mus musculus-5	Stimulation of GTPase activity	10224115 \| 15251227 \| 16380086
59	EFF1237	Tubulin-Mus musculus-21	Stimulation of GTPase activity	10224115 \| 15251227 \| 16380086
60	EFF1238	Tubulin-Mus musculus-20	Stimulation of GTPase activity	10224115 \| 15251227 \| 16380086
61	EFF1239	Tubulin-Mus musculus-18	Stimulation of GTPase activity	10224115 \| 15251227 \| 16380086
62	EFF1240	Tubulin-Mus musculus-17	Stimulation of GTPase activity	10224115 \| 15251227 \| 16380086
63	EFF1241	Tubulin-Mus musculus-16	Stimulation of GTPase activity	10224115 \| 15251227 \| 16380086
64	EFF1242	Tubulin-Mus musculus-15	Stimulation of GTPase activity	10224115 \| 15251227 \| 16380086
65	EFF1243	Tubulin-Mus musculus-14	Stimulation of GTPase activity	10224115 \| 15251227 \| 16380086
66	EFF1244	Tubulin-Mus musculus-13	Stimulation of GTPase activity	10224115 \| 15251227 \| 16380086
67	EFF1245	Tubulin-Mus musculus-6	Stimulation of GTPase activity	10224115 \| 15251227 \| 16380086
68	EFF1246	Tubulin-Mus musculus-7	Stimulation of GTPase activity	10224115 \| 15251227 \| 16380086
69	EFF1247	Tubulin-Mus musculus-8	Stimulation of GTPase activity	10224115 \| 15251227 \| 16380086
70	EFF1248	Tubulin-Mus musculus-9	Stimulation of GTPase activity	10224115 \| 15251227 \| 16380086

Coupling with GPCRs:
1	GPCR0091	5-HYDROXYTRYPTAMINE RECEPTOR_5-HT-4_Mus musculus	2849052
2	GPCR0100	5-HYDROXYTRYPTAMINE RECEPTOR_5-HT-6_Mus musculus	8522988
3	GPCR0105	5-HYDROXYTRYPTAMINE RECEPTOR_5-HT-7_Mus musculus	8397408
4	GPCR0184	ADENOSINE RECEPTOR_A2A_Mus musculus	1662665
5	GPCR0233	ADRENOCEPTOR (A2-ADRENOCEPTOR)_A2A(Adrenoceptor)_Mus musculus	8662784
6	GPCR0186	ADENOSINE RECEPTOR_A2B_Mus musculus	11048721
7	GPCR2571	CALCITONIN, AMYLIN, CGRP, AND ADRENOMEDULIN RECEPTOR_ADRENOMEDULIN RECEPTOR_Mus musculus	8549809
8	GPCR0306	ADRENOCEPTOR (B-ADRENOCEPTOR)_B1(Adrenoceptor)_Mus musculus-1	2825170
9	GPCR0314	ADRENOCEPTOR (B-ADRENOCEPTOR)_B1(Adrenoceptor)_Mus musculus-2	2825170
10	GPCR0322	ADRENOCEPTOR (B-ADRENOCEPTOR)_B2(Adrenoceptor)_Mus musculus-2	3041227
11	GPCR0357	ADRENOCEPTOR (B-ADRENOCEPTOR)_B2(Adrenoceptor)_Mus musculus-1	3041227
12	GPCR0400	ADRENOCEPTOR (B-ADRENOCEPTOR)_B3(Adrenoceptor)_Mus musculus	2570461
13	GPCR2575	CALCITONIN, AMYLIN, CGRP, AND ADRENOMEDULIN RECEPTOR_CALCITONIN_Mus musculus	1331173
14	GPCR0733	CHOLECYSTOKININ AND GASTRIN RECEPTOR_CCK1_Mus musculus	8503909
15	GPCR2581	CALCITONIN, AMYLIN, CGRP, AND ADRENOMEDULIN RECEPTOR_CGRP_Mus musculus	2542467
16	GPCR2585	CORTICOTROPIN-RELEASING FACTOR RECEPTOR_CRF1_Mus musculus	1280419
17	GPCR2589	CORTICOTROPIN-RELEASING FACTOR RECEPTOR_CRF2_Mus musculus	8536644
18	GPCR0752	DOPAMINE RECEPTOR_D1_Mus musculus-2	2144334
19	GPCR0761	DOPAMINE RECEPTOR_D1_Mus musculus-1	2144334
20	GPCR2416	PROSTANOID RECEPTOR_DP_Mus musculus	7512962
21	GPCR2424	PROSTANOID RECEPTOR_EP2_Mus musculus	7910583
22	GPCR2430	PROSTANOID RECEPTOR_EP3_Mus musculus	11095474
23	GPCR2437	PROSTANOID RECEPTOR_EP4_Mus musculus	8016385
24	GPCR0815	ENDOTHELIN RECEPTOR_ET-A_Mus musculus	1849646
25	GPCR0852	GLYCOPROTEIN HORMONE RECEPTOR_FSH RECEPTOR_Mus musculus	9139796
26	GPCR2600	GLUCAGON RECEPTOR_GLUCAGON-LIKE PEPTIDE RECEPTOR_Mus musculus	1326760
27	GPCR2596	GLUCAGON RECEPTOR_GLUCAGON RECEPTOR_Mus musculus	8144028
28	GPCR0971	HISTAMINE RECEPTOR_H2_Mus musculus-1	1703298
29	GPCR0973	HISTAMINE RECEPTOR_H2_Mus musculus-2	1703298
30	GPCR0975	HISTAMINE RECEPTOR_H2_Mus musculus-4	1703298
31	GPCR0979	HISTAMINE RECEPTOR_H2_Mus musculus-3	1703298
32	GPCR2444	PROSTANOID RECEPTOR_IP_Mus musculus	7512962
33	GPCR0877	GLYCOPROTEIN HORMONE RECEPTOR_LSH RECEPTOR_Mus musculus	1516719
34	GPCR1168	MELANOCORTIN RECEPTOR_MC1_Mus musculus	1516719
35	GPCR1180	MELANOCORTIN RECEPTOR_MC2_Mus musculus	1325670
36	GPCR1190	MELANOCORTIN RECEPTOR_MC3_Mus musculus	8463333
37	GPCR1193	MELANOCORTIN RECEPTOR_MC4_Mus musculus	8392067
38	GPCR1208	MELANOCORTIN RECEPTOR_MC5_Mus musculus	8185570
39	GPCR2500	TACHYKININ RECEPTOR_NK1_Mus musculus	1370820
40	GPCR2508	TACHYKININ RECEPTOR_NK2_Mus musculus	1370820
41	GPCR2512	TACHYKININ RECEPTOR_NK3_Mus musculus	1370820
42	GPCR2619	VASOACTIVE INTESTINAL PEPTIDE AND PITUITARY ADENYLATE CYCLASE ACTIVATING PEPTIDE RECEPTOR_PAC1_Mus musculus	8396727
43	GPCR2612	PARATHYROID HORMONE RECEPTOR_PARATHYROID HORMONE/PARATHYROID HORMONE-RELATED PEPTIDE RECEPTOR_Mus musculus	1658941
44	GPCR1105	LYSOPHOSPHOLIPID RECEPTOR_S1P-like_Mus musculus-3	12220620
45	GPCR1114	LYSOPHOSPHOLIPID RECEPTOR_S1P-like_Mus musculus-1	12220620
46	GPCR1123	LYSOPHOSPHOLIPID RECEPTOR_S1P-like_Mus musculus-2	12220620
47	GPCR1128	LYSOPHOSPHOLIPID RECEPTOR_S1P-like_Mus musculus-4	12220620
48	GPCR1129	TRACE AMINE RECEPTOR_TaR_Mus musculus	11459929
49	GPCR2531	TRACE AMINE RECEPTOR_TaR-1_Mus musculus	11459929
50	GPCR0897	GLYCOPROTEIN HORMONE RECEPTOR_TSH RECEPTOR_Mus musculus-1	8552586
51	GPCR2624	VASOACTIVE INTESTINAL PEPTIDE AND PITUITARY ADENYLATE CYCLASE ACTIVATING PEPTIDE RECEPTOR_VPAC1_Mus musculus-1	1675791
52	GPCR2628	VASOACTIVE INTESTINAL PEPTIDE AND PITUITARY ADENYLATE CYCLASE ACTIVATING PEPTIDE RECEPTOR_VPAC1_Mus musculus-2	1675791
53	GPCR2635	VASOACTIVE INTESTINAL PEPTIDE AND PITUITARY ADENYLATE CYCLASE ACTIVATING PEPTIDE RECEPTOR_VPAC2_Mus musculus	7733904


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	University of Athens Faculty of Biology Dept. of Cell Biology and Biophysics	Biophysics & Bioinformatics Laboratory