gpDB: a database of GPCRs, G-proteins, Effectors and their interactions
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gpDB::GPCR View
Entry 1 of 1 :: GPCR2590 ::
CLASS CLASS B (SECRETIN LIKE)
FAMILY CORTICOTROPIN-RELEASING FACTOR RECEPTOR
SUBFAMILY CRF2

Cross References:
UniProt P47866 EMBL U16253
InterPro IPR003053 | IPR003051 | IPR001879 | IPR000832 GPCRDB CRFR2_RAT
GENEID 64680
PRINTS PR01279 | PR01281 | PR00249 PFAM PF00002 | PF02793

Details:
NAME CORTICOTROPIN-RELEASING FACTOR RECEPTOR_CRF2_Rattus norvegicus
DESCRIPTION Corticotropin-releasing factor receptor 2 precursor (CRF-R 2) (CRF2)(Corticotropin-releasing hormone receptor 2) (CRH-R 2).
SPECIES Rattus norvegicus COMMON NAME Rat NCBI Taxonomy 10116
GENE Crhr2 | Crf2r
SEQUENCE
MDAALLLSLLEANCSLALAEELLLDGWGEPPDPEGPYSYCNTTLDQIGTCWPQSAPGALV
ERPCPEYFNGIKYNTTRNAYRECLENGTWASRINYSHCEPILDDKQRKYDLHYRIALIIN
YLGHCVSVVALVAAFLLFLVLRSIRCLRNVIHWNLITTFILRNITWFLLQLIDHEVHEGN
EVWCRCVTTIFNYFVVTNFFWMFVEGCYLHTAIVMTYSTEHLRKWLFLFIGWCIPCPIIV
AWAVGKLYYENEQCWFGKEPGDLVDYIYQGPIILVLLINFVFLFNIVRILMTKLRASTTS
ETIQYRKAVKATLVLLPLLGITYMLFFVNPGEDDLSQIVFIYFNSFLQSFQGFFVSVFYC
FFNGEVRSALRKRWHRWQDHHALRVPVARAMSIPTSPTRISFHSIKQTAAV
FRAGMENT NO

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Coupling with G-proteins:
Family:Gs REFERENCES:8536644
1GPR0124Galpha-s-Rattus norvegicus-2
2GPR0392Galpha-s-Rattus norvegicus-1


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athina University of Athens
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Biophysics
& Bioinformatics
Laboratory