gpDB: a database of GPCRs, G-proteins, Effectors and their interactions
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gpDB::GPCR View
Entry 1 of 1 :: GPCR2609 ::
CLASS CLASS B (SECRETIN LIKE)
FAMILY PARATHYROID HORMONE RECEPTOR
SUBFAMILY PARATHYROID HORMONE RECEPTOR

Cross References:
UniProt P70555 EMBL U55836
InterPro IPR001879 | IPR000832 GPCRDB PTH2R_RAT
GENEID 81753
PRINTS PR00249 PFAM PF00002 | PF02793

Details:
NAME PARATHYROID HORMONE RECEPTOR_PARATHYROID HORMONE RECEPTOR_Rattus norvegicus
DESCRIPTION Parathyroid hormone 2 receptor precursor (PTH2 receptor).
SPECIES Rattus norvegicus COMMON NAME Rat NCBI Taxonomy 10116
GENE Pth2r | Pthr2
SEQUENCE
MPWLEALPYICGWLILRSCLLVGAQLDSDGTITIEEQIVLVMKAKMQCELNITAQFQEGE
GNCFPEWDGLICWPRGTAGKTSAMPCPSYVYDFNHKGVAFRHCTPNGTWDFIHGSNKTWA
NYSDCFLQPDINIGKQEFFENLYILYTVGYSISFGSLAVAILIIGYFRRLHCTRNYIHLH
LFVSFMLRAXSIFVKDRVAQAHLGVEALQSLVMQGDLQNFIGGPSVDKSQYVGCKIAVVM
FIYFLATNYYWILVEGLYLHNLIFVSFFSDTKYLWGFILIGWGFPAVFVVAWAVARATLA
DTRCWELSAGDRWIYXXPILAAIGLNFILFLNTVRVLATKIWETNAVGHDMRKQYRKLAK
STLVLVLVFGVHYIVFICQPHSFSGLWWEIRMHCELFFNSFQGFFVSIVYCYCNGEVQAE
VKKTWTRWNLSIDWKKAPPCGGHRYGSVLTTVTHSTSSQSQMGPSTRLVLISSKPAKTAC
RQIDSHVTLPGYVWSSSEQDCQPQSTPEETKKGHGRQEDDSPVGESSRPVAFTIDTEGCK
GESHPI
FRAGMENT NO

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Scaffold:
TYPE NHERF1( Na+/H+ exchange regulatory factor) /EBP50( ezrin-radixin-moesin binding phosphoprotein 50-kD protein) REFERENCES 12075354
TYPE NHERF2/E3 KARP REFERENCES 12075354

Coupling with G-proteins:
Family:Gs REFERENCES:7797535
1GPR0124Galpha-s-Rattus norvegicus-2
2GPR0392Galpha-s-Rattus norvegicus-1


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athina University of Athens
Faculty of Biology
Dept. of Cell Biology and Biophysics
Biophysics
& Bioinformatics
Laboratory