gpDB: a database of GPCRs, G-proteins, Effectors and their interactions
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gpDB::GPCR View
Entry 1 of 1 :: GPCR0394 ::
CLASS CLASS A (RHODOPSIN LIKE)
FAMILY ADRENOCEPTOR (B-ADRENOCEPTOR)
SUBFAMILY B3(Adrenoceptor)

Cross References:
UniProt P13945 | Q4JFT4 EMBL M29932 | X72861 | X70811 | X70812 | X70812 | AY487247 | DQ104441 | BC075017 | S53291
InterPro IPR000681 | IPR002233 | IPR000276 PDB 2CDW GPCRDB ADRB3_HUMAN
GENEID 155 MIM 109691
PRINTS PR01103 | PR00563 | PR00237 PFAM PF00001

Details:
NAME ADRENOCEPTOR (B-ADRENOCEPTOR)_B3(Adrenoceptor)_Homo sapiens
DESCRIPTION Beta-3 adrenergic receptor (Beta-3 adrenoceptor) (Beta-3adrenoreceptor).
SPECIES Homo sapiens COMMON NAME Human NCBI Taxonomy 9606
GENE ADRB3 | ADRB3R | B3AR
SEQUENCE 
MAPWPHENSSLAPWPDLPTLAPNTANTSGLPGVPWEAALAGALLALAVLATVGGNLLVIV
AIAWTPRLQTMTNVFVTSLAAADLVMGLLVVPPAATLALTGHWPLGATGCELWTSVDVLC
VTASIETLCALAVDRYLAVTNPLRYGALVTKRCARTAVVLVWVVSAAVSFAPIMSQWWRV
GADAEAQRCHSNPRCCAFASNMPYVLLSSSVSFYLPLLVMLFVYARVFVVATRQLRLLRG
ELGRFPPEESPPAPSRSLAPAPVGTCAPPEGVPACGRRPARLLPLREHRALCTLGLIMGT
FTLCWLPFFLANVLRALGGPSLVPGPAFLALNWLGYANSAFNPLIYCRSPDFRSAFRRLL
CRCGRRLPPEPCAAARPALFPSGVPAARSSPAQPRLCQRLDGASWGVS
 FRAGMENT NO

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Scaffold:
TYPE c-Src REFERENCES 11013230

Coupling with G-proteins:
Family:Gi/o REFERENCES:9363896
1GPR0020Galpha-o1-Homo sapiens
2GPR0109Galpha-i3-Homo sapiens
3GPR0218Galpha-i1-Homo sapiens-1
4GPR0226Galpha-i2-Homo sapiens-2
5GPR0261Galpha-i1-Homo sapiens-2
6GPR0334Galpha-o-Homo sapiens
7GPR0365Galpha-i2-Homo sapiens-1
Family:Gs REFERENCES:2570461
8GPR0119Galpha-s-Homo sapiens-2
9GPR0263Galpha-s-Homo sapiens-4
10GPR0266Galpha-s-Homo sapiens-5
11GPR0267Galpha-s-Homo sapiens-6
12GPR0277Galpha-s-Homo sapiens-7
13GPR0278Galpha-s-Homo sapiens
14GPR0395Galpha-s-Homo sapiens-3

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athina University of Athens
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 Dept. of Cell Biology and Biophysics
Biophysics
& Bioinformatics
Laboratory