gpDB: a database of GPCRs, G-proteins, Effectors and their interactions
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gpDB::GPCR View
Entry 1 of 1 :: GPCR0818 ::
CLASS CLASS A (RHODOPSIN LIKE)
FAMILY ENDOTHELIN RECEPTOR
SUBFAMILY ET-B

Cross References:
UniProt P24530 | O15343 | Q9UQK3 EMBL M74921 | D90402 | L06623 | S44866 | S57283 | D13168 | X99250 | AF114165 | AY275463 | AY547312 | BC014472
InterPro IPR000499 | IPR001112 | IPR000276 GPCRDB EDNRB_HUMAN
GENEID 1910 MIM 131244 | 142623 | 277580 | 600155 | 600501
PRINTS PR00571 | PR00366 | PR00237 PFAM PF00001

Details:
NAME ENDOTHELIN RECEPTOR_ET-B_Homo sapiens
DESCRIPTION Endothelin B receptor precursor (ET-B) (Endothelin receptor Non-selective type).
SPECIES Homo sapiens COMMON NAME Human NCBI Taxonomy 9606
GENE EDNRB | ETRB
SEQUENCE 
MQPPPSLCGRALVALVLACGLSRIWGEERGFPPDRATPLLQTAEIMTPPTKTLWPKGSNA
SLARSLAPAEVPKGDRTAGSPPRTISPPPCQGPIEIKETFKYINTVVSCLVFVLGIIGNS
TLLRIIYKNKCMRNGPNILIASLALGDLLHIVIDIPINVYKLLAEDWPFGAEMCKLVPFI
QKASVGITVLSLCALSIDRYRAVASWSRIKGIGVPKWTAVEIVLIWVVSVVLAVPEAIGF
DIITMDYKGSYLRICLLHPVQKTAFMQFYKTAKDWWLFSFYFCLPLAITAFFYTLMTCEM
LRKKSGMQIALNDHLKQRREVAKTVFCLVLVFALCWLPLHLSRILKLTLYNQNDPNRCEL
LSFLLVLDYIGINMASLNSCINPIALYLVSKRFKNCFKSCLCCWCQSFEEKQSLEEKQSC
LKFKANDHGYDNFRSSNKYSSS
 FRAGMENT NO

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Scaffold:
TYPE eNOS( endothelial nitric oxide synthase) /cNOS/NOS3 REFERENCES 12842859

Coupling with G-proteins:
Family:G12/13 REFERENCES:10199825
1GPR0034Galpha-12-Homo sapiens
2GPR0037Galpha-13-Homo sapiens
Family:Gi/o REFERENCES:1848367
3GPR0020Galpha-o1-Homo sapiens
4GPR0109Galpha-i3-Homo sapiens
5GPR0218Galpha-i1-Homo sapiens-1
6GPR0226Galpha-i2-Homo sapiens-2
7GPR0261Galpha-i1-Homo sapiens-2
8GPR0334Galpha-o-Homo sapiens
9GPR0365Galpha-i2-Homo sapiens-1
Family:Gq/11 REFERENCES:1848367
10GPR0002Galpha-q-Homo sapiens-2
11GPR0029Galpha-11-Homo sapiens
12GPR0237Galpha-q-Homo sapiens-1

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athina University of Athens
 Faculty of Biology
 Dept. of Cell Biology and Biophysics
Biophysics
& Bioinformatics
Laboratory