gpDB: a database of GPCRs, G-proteins, Effectors and their interactions
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gpDB::GPCR View
Entry 1 of 1 :: GPCR0819 ::
CLASS CLASS A (RHODOPSIN LIKE)
FAMILY ENDOTHELIN RECEPTOR
SUBFAMILY ET-B

Cross References:
UniProt P28088 | Q0VCB3 EMBL D10994 | D90456 | BC120256
InterPro IPR000499 | IPR001112 | IPR000276 GPCRDB EDNRB_BOVIN
GENEID 281750
PRINTS PR00571 | PR00366 | PR00237 PFAM PF00001

Details:
NAME ENDOTHELIN RECEPTOR_ET-B_Bos taurus
DESCRIPTION Endothelin B receptor precursor (ET-B) (Endothelin receptor Non-selective type).
SPECIES Bos taurus COMMON NAME Bovine NCBI Taxonomy 9913
GENE EDNRB
SEQUENCE
MQPLPSLCGRALVALILACGVAGIQAEEREFPPAGATQPLPGTGEMMETPTETSWPGRSN
ASDPRSSATPQIPRGGRMAGIPPRTPPPCDGPIEIKETFKYINTVVSCLVFVLGIIGNST
LLRIIYKNKCMRNGPNILIASLALGDLLHIIIDIPINTYKLLAKDWPFGVEMCKLVPFIQ
KASVGITVLSLCALSIDRYRAVASWSRIKGIGVPKWTAVEIVLIWVVSVVLAVPEAVGFD
IITSDHIGNKLRICLLHPTQKTAFMQFYKTAKDWWLFSFYFCLPLAITALFYTLMTCEML
RKKSGMQIALNDHLKQRREVAKTVFCLVLVFALCWLPLHLSRILKLTLYDQHDPRRCEFL
SFLLVLDYIGINMASLNSCINPIALYLVSKRFKNCFKSCLCCWCQSFEEKQSLEEKQSCL
KFKANDHGYDNFRSSNKYSSS
FRAGMENT NO

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Scaffold:
TYPE eNOS( endothelial nitric oxide synthase) /cNOS/NOS3 REFERENCES 12842859

Coupling with G-proteins:
Family:Gi/o REFERENCES:1848367
1GPR0017Galpha-o1-Bos taurus
2GPR0219Galpha-i1-Bos taurus
3GPR0294Galpha-i2-Bos taurus-2
4GPR0295Galpha-i2-Bos taurus-1
Family:Gq/11 REFERENCES:1848367
5GPR0027Galpha-11-Bos taurus


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athina University of Athens
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Dept. of Cell Biology and Biophysics
Biophysics
& Bioinformatics
Laboratory