gpDB: a database of GPCRs, G-proteins, Effectors and their interactions
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gpDB::GPCR View
Entry 1 of 1 :: GPCR0905 ::
CLASS CLASS A (RHODOPSIN LIKE)
FAMILY GONADOTROPIN-RELEASING HORMONE RECEPTOR
SUBFAMILY GNRH1

Cross References:
UniProt Q01776 | Q61611 EMBL L01119 | M93108 | L33789 | L33778 | L33788
InterPro IPR015693 | IPR000276 | IPR001658 GPCRDB GNRHR_MOUSE
GENEID 14715
PRINTS PR00529 | PR00237 PFAM PF00001

Details:
NAME GONADOTROPIN-RELEASING HORMONE RECEPTOR_GNRH1_Mus musculus
DESCRIPTION Gonadotropin-releasing hormone receptor (GnRH receptor) (GnRH-R).
SPECIES Mus musculus COMMON NAME Mouse NCBI Taxonomy 10090
GENE Gnrhr
SEQUENCE
MANNASLEQDPNHCSAINNSIPLIQGKLPTLTVSGKIRVTVTFFLFLLSTAFNASFLLKL
QKWTQKRKKGKKLSRMKVLLKHLTLANLLETLIVMPLDGMWNITVQWYAGEFLCKVLSYL
KLFSMYAPAFMMVVISLDRSLAITQPLAVQSNSKLEQSMISLAWILSIVFAGPQLYIFRM
IYLADGSGPTVFSQCVTHCSFPQWWHQAFYNFFTFGCLFIIPLLIMLICNAKIIFALTRV
LHQDPRKLQLNQSKNNIPRARLRTLKMTVAFATSFVVCWTPYYVLGIWYWFDPEMLNRVS
EPVNHFFFLFAFLNPCFDPLIYGYFSL
FRAGMENT NO

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Dimerization:
HOMODIMER INFORMATION There is experimental evidence for homo-dimerization METHOD Bioluminescence Resonance Energy Transfer (BRET) REFERENCES 11278883
HOMODIMER INFORMATION There is experimental evidence for homo-dimerization METHOD Photobleaching Fluorescence Resonance Energy Transfer (FRET) REFERENCES 11035030 | 11328852

Coupling with G-proteins:
Family:Gq/11 REFERENCES:1333190
1GPR0031Galpha-11-Mus musculus-2
2GPR0240Galpha-q-Mus musculus
3GPR0360Galpha-11-Mus musculus-1


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athina University of Athens
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Biophysics
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Laboratory