gpDB: a database of GPCRs, G-proteins, Effectors and their interactions
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gpDB::GPCR View
Entry 1 of 1 :: GPCR0973 ::
CLASS CLASS A (RHODOPSIN LIKE)
FAMILY HISTAMINE RECEPTOR
SUBFAMILY H2

Cross References:
UniProt Q9QX37 EMBL AF019138 | AF513034 | AF513035
InterPro IPR000276 | IPR000503 GPCRDB Q9QX37_MOUSE
GENEID 15466
PRINTS PR00237 | PR00531 PFAM PF00001

Details:
NAME HISTAMINE RECEPTOR_H2_Mus musculus-2
DESCRIPTION Histamine H2 receptor (Histamine receptor H2).
SPECIES Mus musculus COMMON NAME Mouse NCBI Taxonomy 10090
GENE Hrh2
SEQUENCE
MEPNGTVHSCCLDSIALKVTISVVLTTLIFITVAGNVVVCLAVSLNRRLRSLTNCFIVSL
AATDLLLGLLVMPFSAIYQLSFKWSFGQVFCNIYTSLDVMLCTASILNLFMISLDRYCAV
TDPLRYPVLVTPVRVAISLVFIWVISITLSFLSIHLGWNSRNGTRGGNDTFKCKVQVNEV
YGLVDGMVTFYLPLLIMCVTYYRIFKIAREQAKRINHISSWKAATIREHKATVTLAAVMG
AFIVCWFPYFTAFVYRGLRGDDAVNEVVEGIVLWLGYANSALNPILYATLNRDFRMAYQQ
LFHCKLASHNSHKTSLRLNNSLLSRSQSREGRWQEEKPLKLQVWSGTELTHPQGSPVR
FRAGMENT NO

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Dimerization:
HOMODIMER INFORMATION There is experimental evidence for homo-dimerization METHOD Immunoprecipitation REFERENCES 9202162

Coupling with G-proteins:
Family:Gs REFERENCES:1703298
1GPR0123Galpha-s-Mus musculus-2
2GPR0391Galpha-s-Mus musculus


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athina University of Athens
Faculty of Biology
Dept. of Cell Biology and Biophysics
Biophysics
& Bioinformatics
Laboratory