gpDB: a database of GPCRs, G-proteins, Effectors and their interactions
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gpDB::GPCR View
Entry 1 of 1 :: GPCR0979 ::
CLASS CLASS A (RHODOPSIN LIKE)
FAMILY HISTAMINE RECEPTOR
SUBFAMILY H2

Cross References:
UniProt Q9D282 EMBL AK020259 | AK163760
InterPro IPR000276 | IPR000503 GPCRDB Q9D282_MOUSE
GENEID 15466
PRINTS PR00237 | PR00531 PFAM PF00001

Details:
NAME HISTAMINE RECEPTOR_H2_Mus musculus-3
DESCRIPTION Adult male cecum cDNA, RIKEN full-length enriched library,clone:9130001K16 product:HISTAMINE RECEPTOR H 2, full insert sequence(Adult male corpus striatum cDNA, RIKEN full-length enriched library,clone:C030041E02 product:histamine receptor H 2, full insertsequence).
SPECIES Mus musculus COMMON NAME Mouse NCBI Taxonomy 10090
GENE Hrh2
SEQUENCE
MEPNGTVHSCCLDSIALKVTISVVLTTLIFITVAGNVVVCLAVSLNRRLRSLTNCFIVSL
AATDLLLGLLVMPFSAIYQLSFKWSFGQVFCNIYTSLDVMLCTASILNLFMISLDRYCAV
TDPLRYPVLVTPVRVAISLVFIWVISITLSFLSIHLGWNSRNGTRGGNDTFKCKVQVNEV
YGLVDGMVTFYLPLLIMCVTYYRIFKIAREQAKRINHISSWKAATIREHKATVTLAAVMG
AFIVCWFPYFTAFVYRGLRGDDAVNEVVEGIVLWLGYANSALNPILYATLNRDFRMAYQQ
LFHCKLASHNSHKTSLRLNNSLLSRSQSREGRWQEEKPLKLQVWSGTELTHPQGSPVRTR
LSHSSCLLSLSLLSFIWKLGTWIHHRRPFQPSLHISA
FRAGMENT NO

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Dimerization:
HOMODIMER INFORMATION There is experimental evidence for homo-dimerization METHOD Immunoprecipitation REFERENCES 9202162

Coupling with G-proteins:
Family:Gs REFERENCES:1703298
1GPR0123Galpha-s-Mus musculus-2
2GPR0391Galpha-s-Mus musculus


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athina University of Athens
Faculty of Biology
Dept. of Cell Biology and Biophysics
Biophysics
& Bioinformatics
Laboratory