gpDB::G-protein View

CLASS	Galpha
FAMILY	Gs
SUBFAMILY	Galpha-s
TYPE	Galpha-s

Cross References:
UniProt	P24799	EMBL	X56091
InterPro	IPR001019 \| IPR000367 \| IPR011025
PRODOM	PD000281
GENEID	394414
PRINTS	PR00318 \| PR00443	PFAM	PF00503

Details:
NAME	Galpha-s-Xenopus laevis
DESCRIPTION	Guanine nucleotide-binding protein G(s) subunit alpha (Adenylatecyclase-stimulating G alpha protein).
SPECIES	Xenopus laevis	COMMON NAME	African clawed frog	NCBI Taxonomy	8355
POST TRANSLATION MODIFICATIONS	null	GENE	gnas
SEQUENCE	MGCLGNSKTEDQRNEEKVQRETNKKIEKQLQKDKQVYRATHRLLLLGAGESGKSSIVKQM RILHVNGFNAEEKKTKVQDIKNNIKEAIETIVTAMGNLSPPVELVNPENQFRIDYILNLP NYKDFEFSPEFYEHTKTLWQDEGVRACYERSNEYQLIDCAQYFLDKIDIVKQNDYTPSDQ DLLRCRVLTSGIFETKFQVDKVNFHMFDVGGQRDERRKWIQCFNDVTAIIFVVASSSYNM VIREDNHTNRLQEALNLFKSIWNNRWLRTISVILFLNKQDLLAEKVNAGKSKIEDYFPEF ARYTTPDDATPEVGEDPRVTRAKYFIRDEFLRISTASGDGRHYCYPHFTCAVDTENIRRV FNDCRDIIQRMHLRQYELL				FRAGMENT	NO
FUNCTION	Guanine nucleotide-binding proteins (G proteins) ares involved as modulators or transducers in various transmembranes signaling systems

Effectors:
1	EFF0043	Adenylate cyclase-6-Xenopus laevis	Stimulation	15251227 \| 15922020 \| 14993377 \| 11376933
2	EFF0054	Adenylate cyclase-7-Xenopus laevis	Stimulation	15251227 \| 15922020 \| 14993377 \| 11376933
3	EFF0060	Adenylate cyclase-8-Xenopus laevis	Stimulation	15251227 \| 15922020 \| 14993377 \| 11376933
4	EFF0065	Adenylate cyclase-9-Xenopus laevis	Stimulation	15251227 \| 15922020 \| 14993377 \| 11376933
5	EFF0871	Src tyrosine kinase-Xenopus laevis	Stimulation	11007482 \| 15251227 \| 12209124
6	EFF1382	Tubulin-Xenopus laevis-1	Stimulation of GTPase activity	10224115 \| 15251227 \| 16380086
7	EFF1384	Tubulin-Xenopus laevis-11	Stimulation of GTPase activity	10224115 \| 15251227 \| 16380086
8	EFF1385	Tubulin-Xenopus laevis-12	Stimulation of GTPase activity	10224115 \| 15251227 \| 16380086
9	EFF1386	Tubulin-Xenopus laevis-13	Stimulation of GTPase activity	10224115 \| 15251227 \| 16380086
10	EFF1387	Tubulin-Xenopus laevis-14	Stimulation of GTPase activity	10224115 \| 15251227 \| 16380086
11	EFF1388	Tubulin-Xenopus laevis-15	Stimulation of GTPase activity	10224115 \| 15251227 \| 16380086
12	EFF1389	Tubulin-Xenopus laevis-16	Stimulation of GTPase activity	10224115 \| 15251227 \| 16380086
13	EFF1390	Tubulin-Xenopus laevis-17	Stimulation of GTPase activity	10224115 \| 15251227 \| 16380086
14	EFF1391	Tubulin-Xenopus laevis-18	Stimulation of GTPase activity	10224115 \| 15251227 \| 16380086
15	EFF1392	Tubulin-Xenopus laevis-19	Stimulation of GTPase activity	10224115 \| 15251227 \| 16380086
16	EFF1393	Tubulin-Xenopus laevis-2	Stimulation of GTPase activity	10224115 \| 15251227 \| 16380086
17	EFF1394	Tubulin-Xenopus laevis-20	Stimulation of GTPase activity	10224115 \| 15251227 \| 16380086
18	EFF1395	Tubulin-Xenopus laevis-21	Stimulation of GTPase activity	10224115 \| 15251227 \| 16380086
19	EFF1396	Tubulin-Xenopus laevis-22	Stimulation of GTPase activity	10224115 \| 15251227 \| 16380086
20	EFF1397	Tubulin-Xenopus laevis-23	Stimulation of GTPase activity	10224115 \| 15251227 \| 16380086
21	EFF1398	Tubulin-Xenopus laevis-24	Stimulation of GTPase activity	10224115 \| 15251227 \| 16380086
22	EFF1399	Tubulin-Xenopus laevis-25	Stimulation of GTPase activity	10224115 \| 15251227 \| 16380086
23	EFF1400	Tubulin-Xenopus laevis-26	Stimulation of GTPase activity	10224115 \| 15251227 \| 16380086
24	EFF1401	Tubulin-Xenopus laevis-27	Stimulation of GTPase activity	10224115 \| 15251227 \| 16380086
25	EFF1402	Tubulin-Xenopus laevis-28	Stimulation of GTPase activity	10224115 \| 15251227 \| 16380086
26	EFF1403	Tubulin-Xenopus laevis-10	Stimulation of GTPase activity	10224115 \| 15251227 \| 16380086
27	EFF1404	Tubulin-Xenopus laevis-3	Stimulation of GTPase activity	10224115 \| 15251227 \| 16380086
28	EFF1405	Tubulin-Xenopus laevis-9	Stimulation of GTPase activity	10224115 \| 15251227 \| 16380086
29	EFF1406	Tubulin-Xenopus laevis-4	Stimulation of GTPase activity	10224115 \| 15251227 \| 16380086
30	EFF1407	Tubulin-Xenopus laevis-5	Stimulation of GTPase activity	10224115 \| 15251227 \| 16380086
31	EFF1408	Tubulin-Xenopus laevis-6	Stimulation of GTPase activity	10224115 \| 15251227 \| 16380086
32	EFF1409	Tubulin-Xenopus laevis-7	Stimulation of GTPase activity	10224115 \| 15251227 \| 16380086
33	EFF1410	Tubulin-Xenopus laevis-8	Stimulation of GTPase activity	10224115 \| 15251227 \| 16380086

Coupling with GPCRs:
1	GPCR0107	5-HYDROXYTRYPTAMINE RECEPTOR_5-HT-7_Xenopus laevis	8397408
2	GPCR0305	ADRENOCEPTOR (B-ADRENOCEPTOR)_B1(Adrenoceptor)_Xenopus laevis	2825170
3	GPCR0736	CHOLECYSTOKININ AND GASTRIN RECEPTOR_CCK1_Xenopus laevis	8503909
4	GPCR2583	CORTICOTROPIN-RELEASING FACTOR RECEPTOR_CRF1_Xenopus laevis	1280419
5	GPCR2591	CORTICOTROPIN-RELEASING FACTOR RECEPTOR_CRF2_Xenopus laevis	8536644
6	GPCR0754	DOPAMINE RECEPTOR_D1_Xenopus laevis-2	2144334
7	GPCR0760	DOPAMINE RECEPTOR_D1_Xenopus laevis-1	2144334
8	GPCR0805	DOPAMINE RECEPTOR_D5_Xenopus laevis	1831904
9	GPCR0857	GLYCOPROTEIN HORMONE RECEPTOR_FSH RECEPTOR_Xenopus laevis	9139796
10	GPCR0876	GLYCOPROTEIN HORMONE RECEPTOR_LSH RECEPTOR_Xenopus laevis	1516719


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	University of Athens Faculty of Biology Dept. of Cell Biology and Biophysics	Biophysics & Bioinformatics Laboratory