gpDB: a database of GPCRs, G-proteins, Effectors and their interactions
Introduction Navigation Text Search Blast Search Pattern Search User Manual

gpDB::G-protein View
Entry 1 of 1 :: GPR0041 ::
CLASS Galpha
FAMILY Gq/11
SUBFAMILY Galpha-14
TYPE Galpha-14

Cross References:
UniProt P30677 EMBL M80631 | M57616
InterPro IPR001019 | IPR000654 | IPR011025
PRODOM PD000281
PRINTS PR00318 | PR00442 PFAM PF00503

Details:
NAME Galpha-14-Mus musculus-2
DESCRIPTION Guanine nucleotide-binding protein alpha-14 subunit.
SPECIES Mus musculus COMMON NAME Mouse NCBI Taxonomy 10090
POST TRANSLATION MODIFICATIONS null GENE Gna14 | Gna-14
SEQUENCE
MAGCCCLSAEEKESQRISAEIERHVRRDKKDARRELKLLLLGTGESGKSTFIKQMRIIHG
SGYSDEDRKGFTKLVYQNIFTAMQAMIRAMDTLRIQYMCEQNKENAQIIREVEVDKVTAL
SRDQVAAIKQLWLDPGIQECYDRRREYQLSDSAKYYLTDIERIAMPSFVPTQQDVLRVRV
PTTGIIEYPFDLENIIFRMVDVGGQRSERRKWIHCFESVTSIIFLVALSEYDQVLAECDN
ENRMEESKALFRTIITYPWFLNSSVILFLNKKDLLEEKIMYSHLISYFPEYTGPKQDVKA
ARDFILKLYQDQNPDKEKVIYSHFTCATDTENIRFVFAAVKDTILQLNLREFNLV
FRAGMENT NO
FUNCTION Guanine nucleotide-binding proteins (G proteins) ares involved as modulators or transducers in various transmembranes signaling systems
Effectors:
1EFF0352GRK2-Mus musculus-1Inhibits PLC-beta activation and blocks Gqa-mediated GLUT4 translocation and glucose uptake in 3T3 adipocytes15251227 | 14654303 | 16182515
2EFF0353GRK2-Mus musculus-2Inhibits PLC-beta activation and blocks Gqa-mediated GLUT4 translocation and glucose uptake in 3T3 adipocytes15251227 | 14654303 | 16182515
3EFF0354GRK2-Mus musculus-3Inhibits PLC-beta activation and blocks Gqa-mediated GLUT4 translocation and glucose uptake in 3T3 adipocytes15251227 | 14654303 | 16182515
4EFF0355GRK2-Mus musculus-4Inhibits PLC-beta activation and blocks Gqa-mediated GLUT4 translocation and glucose uptake in 3T3 adipocytes15251227 | 14654303 | 16182515
5EFF0523Phospholipase C beta-1-Mus musculus-1Stimulation of PLC-beta catalytic activity15251227 | 16182515 | 11015615
6EFF0524Phospholipase C beta-1-Mus musculus-2Stimulation of PLC-beta catalytic activity15251227 | 16182515 | 11015615
7EFF0525Phospholipase C beta-1-Mus musculus-3Stimulation of PLC-beta catalytic activity15251227 | 16182515 | 11015615
8EFF0526Phospholipase C beta-1-Mus musculus-4Stimulation of PLC-beta catalytic activity15251227 | 16182515 | 11015615
9EFF0527Phospholipase C beta-1-Mus musculus-5Stimulation of PLC-beta catalytic activity15251227 | 16182515 | 11015615
10EFF0532Phospholipase C beta-2-Mus musculus-1Stimulation of PLC-beta catalytic activity15251227 | 16182515 | 11015615
11EFF0533Phospholipase C beta-2-Mus musculus-2Stimulation of PLC-beta catalytic activity15251227 | 16182515 | 11015615
12EFF0535Phospholipase C beta-2-Mus musculus-3Stimulation of PLC-beta catalytic activity15251227 | 16182515 | 11015615
13EFF0537Phospholipase C beta-2-Mus musculus-4Stimulation of PLC-beta catalytic activity15251227 | 16182515 | 11015615
14EFF0543Phospholipase C beta-3-Mus musculus-1Stimulation of PLC-beta catalytic activity15251227 | 16182515 | 11015615
15EFF0544Phospholipase C beta-3-Mus musculus-2Stimulation of PLC-beta catalytic activity15251227 | 16182515 | 11015615
16EFF0545Phospholipase C beta-3-Mus musculus-3Stimulation of PLC-beta catalytic activity15251227 | 16182515 | 11015615
17EFF0546Phospholipase C beta-3-Mus musculus-4Stimulation of PLC-beta catalytic activity15251227 | 16182515 | 11015615
18EFF0547Phospholipase C beta-3-Mus musculus-5Stimulation of PLC-beta catalytic activity15251227 | 16182515 | 11015615
19EFF0548Phospholipase C beta-3-Mus musculus-6Stimulation of PLC-beta catalytic activity15251227 | 16182515 | 11015615
20EFF0549Phospholipase C beta-3-Mus musculus-7Stimulation of PLC-beta catalytic activity15251227 | 16182515 | 11015615
21EFF0550Phospholipase C beta-3-Mus musculus-8Stimulation of PLC-beta catalytic activity15251227 | 16182515 | 11015615
22EFF0551Phospholipase C beta-3-Mus musculus-9Stimulation of PLC-beta catalytic activity15251227 | 16182515 | 11015615
23EFF0564Phospholipase C beta-4-Mus musculus-1Stimulation of PLC-beta catalytic activity15251227 | 16182515 | 11015615
24EFF0565Phospholipase C beta-4-Mus musculus-2Stimulation of PLC-beta catalytic activity15251227 | 16182515 | 11015615
25EFF0566Phospholipase C beta-4-Mus musculus-3Stimulation of PLC-beta catalytic activity15251227 | 16182515 | 11015615
26EFF0567Phospholipase C beta-4-Mus musculus-4Stimulation of PLC-beta catalytic activity15251227 | 16182515 | 11015615
27EFF0568Phospholipase C beta-4-Mus musculus-5Stimulation of PLC-beta catalytic activity15251227 | 16182515 | 11015615

Coupling with GPCRs:
No information




Designed for viewing with Internet Explorer 4 or above, Netscape 6 or above.
contact biodbbiol.uoa.gr
for comments, corrections and
data (sequence) submission.
athina University of Athens
Faculty of Biology
Dept. of Cell Biology and Biophysics
Biophysics
& Bioinformatics
Laboratory