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gpDB::Effector View
Entry 1 of 1 :: EFF0533 ::
FAMILY Phospholipases C
SUBFAMILY Phospholipases C beta
TYPE Phospholipase C beta 2

Cross References:
UniProt A3KGF7 | Q2M4J1 | Q3TER8 | Q8BI81 EMBL AY902324 | AK045469 | AK169442 | AL772255 | AL772255 | AL772255
InterPro IPR000008 | IPR011992 | IPR015359 | IPR013841 | IPR001192 | IPR000909 | IPR001711 | IPR014815
PRODOM PD001202 GENEID 18796
PRINTS PR00390 PFAM PF00168 | PF09279 | PF00388 | PF00387 | PF08703

Details:
NAME Phospholipase C beta-2-Mus musculus-2
DESCRIPTION 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta-2(EC 3.1.4.11) (Phospholipase C-beta-2) (PLC-beta-2).
SPECIES Mus musculus COMMON NAME Mouse NCBI Taxonomy 10090
GENE Plcb2
SEQUENCE 
MSLLNPVLLPPNVKAYLSQGERFIKWDDETSIASPVILRVDPKGYYLYWTYQNQEMEFLD
VTSIRDTRFGKFAKIPKSQKLREVFNMDFPDNHFLLKTLTVVSGPDMVDLTFYNFVSYKE
NVGKDWAEDVLALAKHPMTVNAPRSTFLDKILVKLKMQLNPEGKIPVKNFFQMFPADRKR
VEAALGACHLAKGKNDAINPEDFPESVYKSFLMSLCPRPEIDEIFTSYHSKAKPYMTKEH
LTKFINQKQRDPRLN
 FRAGMENT NO
FUNCTION The production of the second messenger moleculess diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) iss mediated by activated phosphatidylinositol-specific phospholipases C enzymes
Interacting with G-proteins:
Family:Gq/11 REFERENCES:15251227 | 16182515 | 11015615
1GPR0031Galpha-11-Mus musculus-2
2GPR0360Galpha-11-Mus musculus-1
3GPR0041Galpha-14-Mus musculus-2
4GPR0322Galpha-14-Mus musculus-3
5GPR0324Galpha-14-Mus musculus-4
6GPR0350Galpha-14-Mus musculus-1
7GPR0044Galpha-15-Mus musculus
8GPR0240Galpha-q-Mus musculus
Family:Gbeta REFERENCES:15251227 | 11015615 | 8383116
9GPR0148Gbeta-1-Mus musculus
10GPR0156Gbeta-2-Mus musculus
11GPR0161Gbeta-3-Mus musculus
12GPR0165Gbeta-4-Mus musculus
13GPR0168Gbeta-5-Mus musculus-2
14GPR0291unclassified_Gbeta-Mus musculus-1
15GPR0318unclassified_Gbeta-Mus musculus-2
16GPR0376Gbeta-5-Mus musculus-3
17GPR0377Gbeta-5-Mus musculus-1
Family:Ggamma REFERENCES:15251227 | 11015615 | 8383116
18GPR0178Ggamma-t1-Mus musculus
19GPR0181Ggamma-2-Mus musculus
20GPR0184Ggamma-3-Mus musculus
21GPR0186Ggamma-4-Mus musculus
22GPR0189Ggamma-5-Mus musculus
23GPR0193Ggamma-7-Mus musculus
24GPR0196Ggamma-8-Mus musculus-2
25GPR0200Ggamma-11-Mus musculus
26GPR0204Ggamma-12-Mus musculus
27GPR0206Ggamma-13-Mus musculus
28GPR0211Ggamma-8-Mus musculus-1
29GPR0349Ggamma-1-Mus musculus
30GPR0379Ggamma-10-Mus musculus

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athina University of Athens
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