gpDB: a database of GPCRs, G-proteins, Effectors and their interactions
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gpDB::GPCR View
Entry 1 of 1 :: GPCR1009 ::
CLASS CLASS A (RHODOPSIN LIKE)
FAMILY LYSOPHOSPHOLIPID RECEPTOR
SUBFAMILY LPA1

Cross References:
UniProt P61793 | O88584 | P56487 | P70420 | Q61130 EMBL U70622 | U48235 | AF075456 | AF075453 | AF075455 | AF075456 | AF075455 | BC025425
InterPro IPR002277 | IPR000276 | IPR004065 GPCRDB EDG2_MOUSE
PRINTS PR01148 | PR00237 | PR01527 PFAM PF00001

Details:
NAME LYSOPHOSPHOLIPID RECEPTOR_LPA1_Mus musculus
DESCRIPTION Lysophosphatidic acid receptor Edg-2 (LPA receptor 1) (LPA-1) (Rec1.3)(VZG-1).
SPECIES Mus musculus COMMON NAME Mouse NCBI Taxonomy 10090
GENE Edg2 | Gpcr26 | Lpa1 | Vzg1
SEQUENCE
MAAASTSSPVISQPQFTAMNEQQCFYNESIAFFYNRSGKYLATEWNTVSKLVMGLGITVC
VFIMLANLLVMVAIYVNRRFHFPIYYLMANLAAADFFAGLAYFYLMFNTGPNTRRLTVST
WLLRQGLIDTSLTASVANLLAIAIERHITVFRMQLHTRMSNRRVVVVIVVIWTMAIVMGA
IPSVGWNCICDIDHCSNMAPLYSDSYLVFWAIFNLVTFVVMVVLYAHIFGYVRQRTMRMS
RHSSGPRRNRDTMMSLLKTVVIVLGAFIVCWTPGLVLLLLDVCCPQCDVLAYEKFFLLLA
EFNSAMNPIIYSYRDKEMSATFRQILCCQRNENPNGPTEGSDRSASSLNHTILAGVHSND
HSVV
FRAGMENT NO

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Coupling with G-proteins:
Family:G12/13 REFERENCES:9600933
1GPR0035Galpha-12-Mus musculus
2GPR0038Galpha-13-Mus musculus-2
3GPR0323Galpha-13-Mus musculus-3
4GPR0380Galpha-13-Mus musculus-1
Family:Gi/o REFERENCES:9070858
5GPR0021Galpha-o1-Mus musculus
6GPR0227Galpha-i2-Mus musculus-2
7GPR0289Galpha-i1-Mus musculus
8GPR0331Galpha-i2-Mus musculus-1
9GPR0385Galpha-i3-Mus musculus
Family:Gq/11 REFERENCES:9600933
10GPR0031Galpha-11-Mus musculus-2
11GPR0240Galpha-q-Mus musculus
12GPR0360Galpha-11-Mus musculus-1


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athina University of Athens
Faculty of Biology
Dept. of Cell Biology and Biophysics
Biophysics
& Bioinformatics
Laboratory