gpDB: a database of GPCRs, G-proteins, Effectors and their interactions
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gpDB::GPCR View
Entry 1 of 1 :: GPCR1096 ::
CLASS CLASS A (RHODOPSIN LIKE)
FAMILY LYSOPHOSPHOLIPID RECEPTOR
SUBFAMILY S1P3

Cross References:
UniProt Q9Z0U9 | Q8BP20 EMBL AF108021 | AK028043 | AK029852 | AK030134 | AK047268 | AK081919 | AK084944 | AK085180 | AK078443 | AB028143 | BC064007 | BC068176
InterPro IPR000987 | IPR004062 | IPR000276 | IPR004061 GPCRDB EDG3_MOUSE
GENEID 13610
PRINTS PR01524 | PR00237 | PR01523 PFAM PF00001

Details:
NAME LYSOPHOSPHOLIPID RECEPTOR_S1P3_Mus musculus
DESCRIPTION Sphingosine 1-phosphate receptor Edg-3 (S1P receptor Edg-3)(Endothelial differentiation G-protein coupled receptor 3)(Sphingosine 1-phosphate receptor 3) (S1P3) (Lysophospholipid receptorB3).
SPECIES Mus musculus COMMON NAME Mouse NCBI Taxonomy 10090
GENE Edg3 | Lpb3
SEQUENCE
MATTHAQGHQPVLGNDTLREHYDYVGKLAGRLRDPPEGGTLITTILFLVTCSFIVLENLM
VLIAIWKNNKFHNRMYFFIGNLALCDLLAGIAYKVNILMSGRKTFSLSPTVWFLREGSMF
VALGASTCSLLAIAIERHLTMIKMRPYDANKKHRVFLLIGMCWLIAFSLGALPILGWNCL
ENFPDCSTILPLYSKKYIAFLISIFTAILVTIVILYARIYCLVKSSSRRVANHNSERSMA
LLRTVVIVVSVFIACWSPLFILFLIDVACRAKECSILFKSQWFIMLAVLNSAMNPVIYTL
ASKEMRRAFFRLVCGCLVKGKGTQASPMQPALDPSRSKSSSSNNSSHSPKVKEDLPRVAT
SSCIIDKNRSFQNGVLCK
FRAGMENT NO

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Coupling with G-proteins:
Family:G12/13 REFERENCES:10488065
1GPR0035Galpha-12-Mus musculus
2GPR0038Galpha-13-Mus musculus-2
3GPR0323Galpha-13-Mus musculus-3
4GPR0380Galpha-13-Mus musculus-1
Family:Gi/o REFERENCES:9409733
5GPR0021Galpha-o1-Mus musculus
6GPR0227Galpha-i2-Mus musculus-2
7GPR0289Galpha-i1-Mus musculus
8GPR0331Galpha-i2-Mus musculus-1
9GPR0385Galpha-i3-Mus musculus
Family:Gq/11 REFERENCES:9409733
10GPR0031Galpha-11-Mus musculus-2
11GPR0240Galpha-q-Mus musculus
12GPR0360Galpha-11-Mus musculus-1


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athina University of Athens
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Dept. of Cell Biology and Biophysics
Biophysics
& Bioinformatics
Laboratory