gpDB: a database of GPCRs, G-proteins, Effectors and their interactions
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gpDB::GPCR View
Entry 1 of 1 :: GPCR2411 ::
CLASS CLASS A (RHODOPSIN LIKE)
FAMILY PLATELET ACTIVATING FACTOR (PAF) RECEPTOR
SUBFAMILY PLATELET ACTIVATING FACTOR (PAF) RECEPTOR

Cross References:
UniProt P46002 EMBL U04740 | BC072491
InterPro IPR000276 | IPR002282 GPCRDB PTAFR_RAT
GENEID 58949
PRINTS PR00237 | PR01153 PFAM PF00001

Details:
NAME PLATELET ACTIVATING FACTOR (PAF) RECEPTOR_PLATELET ACTIVATING FACTOR (PAF) RECEPTOR_Rattus norvegicus
DESCRIPTION Platelet-activating factor receptor (PAF-R).
SPECIES Rattus norvegicus COMMON NAME Rat NCBI Taxonomy 10116
GENE Ptafr
SEQUENCE
MEQNGSFRVDSEFRYTLFPIVYSVIFVLGVVANGYVLWVFATLYPSKKLNEIKIFMVNLT
VADLLFLMTLPLWIVYYSNEGDWIVHKFLCNLAGCLFFINTYCSVAFLGVITYNRYQAVA
YPIKTAQATTRKRGITLSLVIWISIAATASYFLATDSTNVVPKKDGSGNITRCFEHYEPY
SVPILVVHIFITSCFFLVFFLIFYCNMVIIHTLLTRPVRQQRKPEVKRRALWMVCTVLAV
FVICFVPHHVVQLPWTLAELGYQTNFHQAINDAHQITLCLLSTNCVLDPVIYCFLTKKFR
KHLSEKFYSMRSSRKCSRATSDTCTEVMMPANQTPVLPLKN
FRAGMENT NO

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Dimerization:
HOMODIMER INFORMATION There is experimental evidence for homo-dimerization METHOD Immunoprecipitation REFERENCES 7929127

Coupling with G-proteins:
Family:Gi/o REFERENCES:7876256
1GPR0026Galpha-o-Rattus norvegicus
2GPR0111Galpha-i3-Rattus norvegicus
3GPR0221Galpha-i1-Rattus norvegicus
4GPR0229Galpha-i2-Rattus norvegicus
Family:Gq/11 REFERENCES:7876256
5GPR0032Galpha-11-Rattus norvegicus
6GPR0242Galpha-q-Rattus norvegicus


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athina University of Athens
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Biophysics
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