gpDB: a database of GPCRs, G-proteins, Effectors and their interactions
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gpDB::GPCR View
Entry 1 of 1 :: GPCR2460 ::
CLASS CLASS A (RHODOPSIN LIKE)
FAMILY PROTEASE-ACTIVATED RECEPTOR
SUBFAMILY PAR2

Cross References:
UniProt Q63645 | Q499T9 EMBL U61373 | BC099765
InterPro IPR000276 | IPR002281 | IPR003912 GPCRDB PAR2_RAT
GENEID 116677
PRINTS PR00237 | PR01428 | PR01152 PFAM PF00001

Details:
NAME PROTEASE-ACTIVATED RECEPTOR_PAR2_Rattus norvegicus
DESCRIPTION Proteinase-activated receptor 2 precursor (PAR-2) (Thrombin receptor-like 1) (Coagulation factor II receptor-like 1).
SPECIES Rattus norvegicus COMMON NAME Rat NCBI Taxonomy 10116
GENE F2rl1 | Par2
SEQUENCE
MRSLSLAWLLGGITLLAASASCNRTVNAPGPNSKGRSLIGRLDTPPPITGKGAPVEPGFS
VDEFSASVLTGKLTTVFLPVIYIIVFVIGLPSNGMALWVFFFRTKKKHPAVIYMANLALA
DLLSVIWFPLKISYHLHGNDWTYGDALCKVLIGFFYGNMYCSILFMTCLSVQRYWVIVNP
MGHSRKRANIAVGVSLAIWLLIFLVTIPLYVMRQTIYIPALNITTCHDVLPEEVLVGDMF
SYFLSLAIGVFLFPALLTASAYVLMIKTLRSSAMDEHSEKKRRRAIRLIITVLSMYFICF
APSNVLLVVHYFLIKSQRQSHVYALYLVALCLSTLNSCIDPFVYYFVSKDFRDQARNALL
CRSVRTVKRMQISLTSNKFSRKSSSYSSSSTSVKTSY
FRAGMENT NO

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Coupling with G-proteins:
Family:Gi/o REFERENCES:15082510
1GPR0026Galpha-o-Rattus norvegicus
2GPR0111Galpha-i3-Rattus norvegicus
3GPR0221Galpha-i1-Rattus norvegicus
4GPR0229Galpha-i2-Rattus norvegicus
Family:Gq/11 REFERENCES:15082510
5GPR0032Galpha-11-Rattus norvegicus
6GPR0242Galpha-q-Rattus norvegicus


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athina University of Athens
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Dept. of Cell Biology and Biophysics
Biophysics
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Laboratory