gpDB: a database of GPCRs, G-proteins, Effectors and their interactions
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gpDB::GPCR View
Entry 1 of 1 :: GPCR2581 ::
CLASS CLASS B (SECRETIN LIKE)
FAMILY CALCITONIN, AMYLIN, CGRP, AND ADRENOMEDULIN RECEPTOR
SUBFAMILY CGRP

Cross References:
UniProt Q9R1W5 | Q9QXH8 | Q9WUP2 EMBL AB015595 | AF146525 | AF209905
InterPro IPR003287 | IPR003289 | IPR001879 | IPR000832 GPCRDB CALRL_MOUSE
GENEID 54598
PRINTS PR01351 | PR01350 | PR00249 PFAM PF00002 | PF02793

Details:
NAME CALCITONIN, AMYLIN, CGRP, AND ADRENOMEDULIN RECEPTOR_CGRP_Mus musculus
DESCRIPTION Calcitonin gene-related peptide type 1 receptor precursor (CGRP type 1receptor) (Calcitonin receptor-like receptor).
SPECIES Mus musculus COMMON NAME Mouse NCBI Taxonomy 10090
GENE Calcrl | Crlr
SEQUENCE
MDKKHILCFLVLLPLNMALISAESEEGVNQTDLGVTRNKIMTAQYECYQKIMQDPIQQAE
GLYCNRTWDGWLCWNDVAAGTESMQYCPDYFQDFDPSEKVTKICDQDGHWFRHPDSNRTW
TNYTLCNNSTHEKVKTALNLFYLTIIGHGLSIASLIISLIIFFYFKSLSCQRITLHKNLF
FSFICNSIVTIIHLTAVANNQALVATNPVSCKVSQFIHLYLMGCNYFWMLCEGVYLHTLI
VVAVFAEKQHLMWYYFLGWGFPLLPACIHAIARSLYYNDNCWISSDTHLLYIIHGPICAA
LLVNLFFLLNIVRVLITKLKVTHQVESNLYMKAVRATLILVPLLGIEFVLFPWRPEGKVA
EEVYDYVMHILMHFQGLLVATIFCFFNGEVQAILRRNWNQYKIQFGNGFSHSDALRSASY
TVSTISDMQGYSHDCPTEHLNGKSIQDIENVALKSENMYDLVM
FRAGMENT NO

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Coupling with G-proteins:
Family:Gq/11 REFERENCES:2536720
1GPR0031Galpha-11-Mus musculus-2
2GPR0240Galpha-q-Mus musculus
3GPR0360Galpha-11-Mus musculus-1
Family:Gs REFERENCES:2542467
4GPR0123Galpha-s-Mus musculus-2
5GPR0391Galpha-s-Mus musculus


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athina University of Athens
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Dept. of Cell Biology and Biophysics
Biophysics
& Bioinformatics
Laboratory