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gpDB::GPCR View
Entry 1 of 1 :: GPCR2730 ::
CLASS FRIZZLED/SMOOTHENED
FAMILY FRIZZLED
SUBFAMILY Frizzled-1

Cross References:
UniProt Q08463 EMBL L02529
InterPro IPR000539 | IPR000024 | IPR015526 | IPR000832 GPCRDB FZD1_RAT
GENEID 58868
PRINTS PR00489 PFAM PF01534 | PF01392

Details:
NAME FRIZZLED_Frizzled-1_Rattus norvegicus
DESCRIPTION Frizzled-1 precursor (Fz-1) (rFz1).
SPECIES Rattus norvegicus COMMON NAME Rat NCBI Taxonomy 10116
GENE Fzd1
SEQUENCE
MAEEAVPSESRAAGRPSLELCAVALPGRREEVGHQDTAGHRRPRAHSRCWARGLLLLLWL
LEAPLLLGVRAQPAGQVSGPGQQRPPPPQPQQGGQQYNGERGISIPDHGYCQPISIPLCT
DIAYNQTIMPNLLGHTNQEDAGLEVHQFYPLVKVQCSAELKFFLCSMYAPVCTVLEQALP
PCRSLCERAQGCEALMNKFGFQWPDTLKCEKFPVHGAGELCVGQNTSDKGTPTPSLLPEF
WTSNPQHGGGGYRGGYPGGAGPVERGKFSCPRALRVPSYLNYHFLGEKDCGAPCEPTKVY
GLMYFGPEELRFSRTWIGIWSVLCCASTLFTVLTYLVDMRRFSYPERPIIFLSGCYTAVA
VAYIAGFLLEDRVVCNDKFAEDGARTVAQGTKKEGCTILFMMLYFFSMASSIWWVILSLT
WFLAAGMKWGHEAIEANSQYFHLAAWAVPAIKTITILALGQVDGDVLSGVCFVGLNNVDA
LRGFVLAPLFVYLFIGTSFLLAGFVSLFRIRTIMKHDGTKTEKLEKLMVRIGVFSVLYTV
PATIVIACYFYEQAFRDQWERSWVAQSCKSYAIPCPHLQGGGGVPPHPPMSPDFTVFMIK
YLMTLIVGITSGFWIWSGKTLNSWRKFYTRLTNSKQGETTV
FRAGMENT NO

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Coupling with G-proteins:
Family:Gi/o REFERENCES:11563835
1GPR0026Galpha-o-Rattus norvegicus
2GPR0111Galpha-i3-Rattus norvegicus
3GPR0221Galpha-i1-Rattus norvegicus
4GPR0229Galpha-i2-Rattus norvegicus
Family:Gq/11 REFERENCES:11563835
5GPR0032Galpha-11-Rattus norvegicus
6GPR0242Galpha-q-Rattus norvegicus


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athina University of Athens
Faculty of Biology
Dept. of Cell Biology and Biophysics
Biophysics
& Bioinformatics
Laboratory