gpDB: a database of GPCRs, G-proteins, Effectors and their interactions
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gpDB::GPCR View
Entry 1 of 1 :: GPCR0817 ::
CLASS CLASS A (RHODOPSIN LIKE)
FAMILY ENDOTHELIN RECEPTOR
SUBFAMILY ET-A

Cross References:
UniProt P26684 EMBL M60786
InterPro IPR000499 | IPR002175 | IPR000276 GPCRDB EDNRA_RAT
GENEID 24326
PRINTS PR00570 | PR00366 | PR00237 PFAM PF00001

Details:
NAME ENDOTHELIN RECEPTOR_ET-A_Rattus norvegicus
DESCRIPTION Endothelin-1 receptor precursor (Endothelin A receptor) (ET-A).
SPECIES Rattus norvegicus COMMON NAME Rat NCBI Taxonomy 10116
GENE Ednra
SEQUENCE
MGVLCFLASFWLALVGGAIADNAERYSANLSSHVEDFTPFPGTEFNFLGTTLQPPNLALP
SNGSMHGYCPQQTKITTAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIA
SLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALS
VDRYRAVASWSRVQGIGIPLITAIEIVSIWILSFILAIPEAIGFVMVPFEYKGEQHRTCM
LNATTKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQ
RREVAKTVFCLVVIFALCWFPLHLSRILKKTVYDEMDKNRCELLSFLLLMDYIGINLATM
NSCINPIALYFVSKKFKNCFQSCLCCCCHQSKSLMTSVPMNGTSIQWKNQEQNHNTERSS
HKDSMN
FRAGMENT NO

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Scaffold:
TYPE beta-arrestin-1 - 2 REFERENCES 11546805

Coupling with G-proteins:
Family:G12/13 REFERENCES:10364236
1GPR0036Galpha-12-Rattus norvegicus
Family:Gq/11 REFERENCES:1849646
2GPR0032Galpha-11-Rattus norvegicus
3GPR0242Galpha-q-Rattus norvegicus
Family:Gs REFERENCES:1849646
4GPR0124Galpha-s-Rattus norvegicus-2
5GPR0392Galpha-s-Rattus norvegicus-1


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athina University of Athens
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Dept. of Cell Biology and Biophysics
Biophysics
& Bioinformatics
Laboratory