gpDB: a database of GPCRs, G-proteins, Effectors and their interactions
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gpDB::GPCR View
Entry 1 of 1 :: GPCR0823 ::
CLASS CLASS A (RHODOPSIN LIKE)
FAMILY ENDOTHELIN RECEPTOR
SUBFAMILY ET-B

Cross References:
UniProt P48302 | Q542M3 EMBL U32329 | AK076426 | AK082103 | AK083415 | AK085532 | BC026553
InterPro IPR000499 | IPR001112 | IPR000276 GPCRDB EDNRB_MOUSE
GENEID 13618
PRINTS PR00571 | PR00366 | PR00237 PFAM PF00001

Details:
NAME ENDOTHELIN RECEPTOR_ET-B_Mus musculus
DESCRIPTION Endothelin B receptor precursor (ET-B) (Endothelin receptor Non-selective type).
SPECIES Mus musculus COMMON NAME Mouse NCBI Taxonomy 10090
GENE Ednrb
SEQUENCE
MQSPASRCGRALVALLLACGFLGVWGEKRGFPPAQATLSLLGTKEVMTPPTKTSWTRGSN
SSLMRSSAPAEVTKGGRGAGVPPRSFPPPCQRNIEISKTFKYINTIVSCLVFVLGIIGNS
TLLRIIYKNKCMRNGPNILIASLALGDLLHIIIDIPINTYKLLAEDWPFGAEMCKLVPFI
QKASVGITVLSLCALSIDRYRAVASWSRIKGIGVPKWTAVEIVLIWVVSVVLAVPEAIGF
DMITSDYKGKPLRVCMLNPFQKTAFMQFYKTAKDWWLFSFYFCLPLAITAVFYTLMTCEM
LRKKSGMQIALNDHLKQRREVAKTVFCLVLVFALCWLPLHLSRILKLTLYDQSNPHRCEL
LSFLLVLDYIGINMASLNSCINPIALYLVSKRFKNCFKSCLCCWCQTFEEKQSLEEKQSC
LKFKANDHGYDNFRSSNKYSSS
FRAGMENT NO

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Scaffold:
TYPE eNOS( endothelial nitric oxide synthase) /cNOS/NOS3 REFERENCES 12842859

Coupling with G-proteins:
Family:G12/13 REFERENCES:10199825
1GPR0035Galpha-12-Mus musculus
2GPR0038Galpha-13-Mus musculus-2
3GPR0323Galpha-13-Mus musculus-3
4GPR0380Galpha-13-Mus musculus-1
Family:Gi/o REFERENCES:1848367
5GPR0021Galpha-o1-Mus musculus
6GPR0227Galpha-i2-Mus musculus-2
7GPR0289Galpha-i1-Mus musculus
8GPR0331Galpha-i2-Mus musculus-1
9GPR0385Galpha-i3-Mus musculus
Family:Gq/11 REFERENCES:1848367
10GPR0031Galpha-11-Mus musculus-2
11GPR0240Galpha-q-Mus musculus
12GPR0360Galpha-11-Mus musculus-1


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athina University of Athens
Faculty of Biology
Dept. of Cell Biology and Biophysics
Biophysics
& Bioinformatics
Laboratory