gpDB: a database of GPCRs, G-proteins, Effectors and their interactions
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gpDB::GPCR View
Entry 1 of 1 :: GPCR0824 ::
CLASS CLASS A (RHODOPSIN LIKE)
FAMILY ENDOTHELIN RECEPTOR
SUBFAMILY ET-B

Cross References:
UniProt P21451 EMBL X57764 | S65355
InterPro IPR000499 | IPR001112 | IPR000276 GPCRDB EDNRB_RAT
GENEID 50672
PRINTS PR00571 | PR00366 | PR00237 PFAM PF00001

Details:
NAME ENDOTHELIN RECEPTOR_ET-B_Rattus norvegicus
DESCRIPTION Endothelin B receptor precursor (ET-B) (Endothelin receptor Non-selective type).
SPECIES Rattus norvegicus COMMON NAME Rat NCBI Taxonomy 10116
GENE Ednrb
SEQUENCE
MQSSASRCGRALVALLLACGLLGVWGEKRGFPPAQATPSLLGTKEVMTPPTKTSWTRGSN
SSLMRSSAPAEVTKGGRVAGVPPRSFPPPCQRKIEINKTFKYINTIVSCLVFVLGIIGNS
TLLRIIYKNKCMRNGPNILIASLALGDLLHIIIDIPINAYKLLAGDWPFGAEMCKLVPFI
QKASVGITVLSLCALSIDRYRAVASWSRIKGIGVPKWTAVEIVLIWVVSVVLAVPEAIGF
DVITSDYKGKPLRVCMLNPFQKTAFMQFYKTAKDWWLFSFYFCLPLAITAIFYTLMTCEM
LRKKSGMQIALNDHLKQRREVAKTVFCLVLVFALCWLPLHLSRILKLTLYDQSNPQRCEL
LSFLLVLDYIGINMASLNSCINPIALYLVSKRFKNCFKSCLCCWCQTFEEKQSLEEKQSC
LKFKANDHGYDNFRSSNKYSSS
FRAGMENT NO

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Scaffold:
TYPE eNOS( endothelial nitric oxide synthase) /cNOS/NOS3 REFERENCES 12842859

Coupling with G-proteins:
Family:G12/13 REFERENCES:10199825
1GPR0036Galpha-12-Rattus norvegicus
Family:Gi/o REFERENCES:1848367
2GPR0026Galpha-o-Rattus norvegicus
3GPR0111Galpha-i3-Rattus norvegicus
4GPR0221Galpha-i1-Rattus norvegicus
5GPR0229Galpha-i2-Rattus norvegicus
Family:Gq/11 REFERENCES:1848367
6GPR0032Galpha-11-Rattus norvegicus
7GPR0242Galpha-q-Rattus norvegicus


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athina University of Athens
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Dept. of Cell Biology and Biophysics
Biophysics
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Laboratory