gpDB: a database of GPCRs, G-proteins, Effectors and their interactions
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gpDB::GPCR View
Entry 1 of 1 :: GPCR0843 ::
CLASS CLASS A (RHODOPSIN LIKE)
FAMILY GLYCOPROTEIN HORMONE RECEPTOR
SUBFAMILY FSH RECEPTOR

Cross References:
UniProt P20395 | Q64183 EMBL L02842 | S81198 | S81117 | S81119 | S81171 | S81121 | S81174 | S81183 | S81194 | S81185 | S81178
InterPro IPR002272 | IPR000276 | IPR002131 | IPR001611 | IPR000372 GPCRDB FSHR_RAT
GENEID 25449
PRINTS PR01143 | PR00373 | PR00237 PFAM PF00001 | PF00560 | PF01462

Details:
NAME GLYCOPROTEIN HORMONE RECEPTOR_FSH RECEPTOR_Rattus norvegicus
DESCRIPTION Follicle-stimulating hormone receptor precursor (FSH-R) (Follitropinreceptor).
SPECIES Rattus norvegicus COMMON NAME Rat NCBI Taxonomy 10116
GENE Fshr
SEQUENCE
MALLLVSLLAFLGTGSGCHHWLCHCSNRVFLCQDSKVTEIPTDLPRNAIELRFVLTKLRV
IPKGSFAGFGDLEKIEISQNDVLEVIEADVFSNLPKLHEIRIEKANNLLYINPEAFQNLP
SLRYLLISNTGIKHLPAVHKIQSLQKVLLDIQDNINIHIVARNSFMGLSFESVILWLSKN
GIEEIHNCAFNGTQLDELNLSDNNNLEELPNDVFQGASGPVILDISRTKVHSLPNHGLEN
LKKLRARSTYRLKKLPNLDKFVTLMEASLTYPSHCCAFANLKRQISELHPICNKSILRQD
IDDMTQIGDQRVSLIDDEPSYGKGSDMMYNEFDYDLCNEVVDVTCSPKPDAFNPCEDIMG
YNILRVLIWFISILAITGNTTVLVVLTTSQYKLTVPRFLMCNLAFADLCIGIYLLLIASV
DIHTKSQYHNYAIDWQTGAGCDAAGFFTVFASELSVYTLTAITLERWHTITHAMQLECKV
QLRHAASVMVLGWTFAFAAALFPIFGISSYMKVSICLPMDIDSPLSQLYVMALLVLNVLA
FVVICGCYTHIYLTVRNPTIVSSSSDTKIAKRMATLIFTDFLCMAPISFFAISASLKVPL
ITVSKAKILLVLFYPINSCANPFLYAIFTKNFRRDFFILLSKFGCYEMQAQIYRTETSSA
THNFHARKSHCSSAPRVTNSYVLVPLNHSSQN
FRAGMENT NO

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Coupling with G-proteins:
Family:Gi/o REFERENCES:9139796
1GPR0026Galpha-o-Rattus norvegicus
2GPR0111Galpha-i3-Rattus norvegicus
3GPR0221Galpha-i1-Rattus norvegicus
4GPR0229Galpha-i2-Rattus norvegicus
Family:Gs REFERENCES:9139796
5GPR0124Galpha-s-Rattus norvegicus-2
6GPR0392Galpha-s-Rattus norvegicus-1


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athina University of Athens
Faculty of Biology
Dept. of Cell Biology and Biophysics
Biophysics
& Bioinformatics
Laboratory