gpDB: a database of GPCRs, G-proteins, Effectors and their interactions
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gpDB::GPCR View
Entry 1 of 1 :: GPCR0089 ::
CLASS CLASS A (RHODOPSIN LIKE)
FAMILY 5-HYDROXYTRYPTAMINE RECEPTOR
SUBFAMILY 5-HT-4

Cross References:
UniProt Q13639 | Q96KH9 | Q96KI0 | Q9H199 | Q9NY73 | Q9UBM6 | Q9UBT4 | Q9UE22 EMBL Y12505 | Y12506 | Y12507 | Y10437 | Y08756 | Y09586 | Y13584 | AJ011371 | AJ243213 | AJ278979 | AJ278981 | AJ278982 | BC074755 | Z48150
InterPro IPR001520 | IPR002233 | IPR000276 GPCRDB 5HT4R_HUMAN
GENEID 3360 MIM 602164
PRINTS PR01059 | PR01103 | PR00237 PFAM PF00001

Details:
NAME 5-HYDROXYTRYPTAMINE RECEPTOR_5-HT-4_Homo sapiens
DESCRIPTION 5-hydroxytryptamine receptor 4 (5-HT-4) (Serotonin receptor 4) (5-HT4).
SPECIES Homo sapiens COMMON NAME Human NCBI Taxonomy 9606
GENE HTR4
SEQUENCE 
MDKLDANVSSEEGFGSVEKVVLLTFLSTVILMAILGNLLVMVAVCWDRQLRKIKTNYFIV
SLAFADLLVSVLVMPFGAIELVQDIWIYGEVFCLVRTSLDVLLTTASIFHLCCISLDRYY
AICCQPLVYRNKMTPLRIALMLGGCWVIPTFISFLPIMQGWNNIGIIDLIEKRKFNQNSN
STYCVFMVNKPYAITCSVVAFYIPFLLMVLAYYRIYVTAKEHAHQIQMLQRAGASSESRP
QSADQHSTHRMRTETKAAKTLCIIMGCFCLCWAPFFVTNIVDPFIDYTVPGQVWTAFLWL
GYINSGLNPFLYAFLNKSFRRAFLIILCCDDERYRRPSILGQTVPCSTTTINGSTHVLRD
AVECGGQWESQCHPPATSPLVAAQPSDT
 FRAGMENT NO

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Coupling with G-proteins:
Family:G12/13 REFERENCES:11923294
1GPR0034Galpha-12-Homo sapiens
2GPR0037Galpha-13-Homo sapiens
Family:Gs REFERENCES:2849052
3GPR0119Galpha-s-Homo sapiens-2
4GPR0263Galpha-s-Homo sapiens-4
5GPR0266Galpha-s-Homo sapiens-5
6GPR0267Galpha-s-Homo sapiens-6
7GPR0277Galpha-s-Homo sapiens-7
8GPR0278Galpha-s-Homo sapiens
9GPR0395Galpha-s-Homo sapiens-3

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athina University of Athens
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 Dept. of Cell Biology and Biophysics
Biophysics
& Bioinformatics
Laboratory