gpDB: a database of GPCRs, G-proteins, Effectors and their interactions
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gpDB::GPCR View
Entry 1 of 1 :: GPCR2427 ::
CLASS CLASS A (RHODOPSIN LIKE)
FAMILY PROSTANOID RECEPTOR
SUBFAMILY EP3

Cross References:
UniProt P34980 | Q63194 | Q64376 EMBL D14869 | D16443 | X80133 | D29969 | X83855
InterPro IPR000154 | IPR000276 | IPR008365 | IPR001244 | IPR000265 GPCRDB PE2R3_RAT
GENEID 24929
PRINTS PR00237 | PR00428 | PR01788 | PR00585 | PR00582 PFAM PF00001

Details:
NAME PROSTANOID RECEPTOR_EP3_Rattus norvegicus
DESCRIPTION Prostaglandin E2 receptor EP3 subtype (Prostanoid EP3 receptor) (PGEreceptor, EP3 subtype).
SPECIES Rattus norvegicus COMMON NAME Rat NCBI Taxonomy 10116
GENE Ptger3
SEQUENCE 
MAGVWAPEHSVEAHSNQSSAADGCGSVSVAFPITMMVTGFVGNALAMLLVVRSYRRRESK
RKKSFLLCIGWLALTDLVGQLLTSPVVILVYLSQRRWEQLDPSGRLCTFFGLTMTVFGLS
SLLVASAMAVERALAIRAPHWYASHMKTRATPVLLGVWLSVLAFALLPVLGVGRYSVQWP
GTWCFISTGPAGNETDSAREPGSVAFASAFACLGLLALVVTFACNLATIKALVSRCRAKA
AASQSSAQWGRITTETAIQLMGIMCVLSVCWSPLLIMMLKMIFNQMSVEQCKTQMGKEKE
CNSFLIAVRLASLNQILDPWVYLLLRKILLRKFCQIRDHTNYASSSTSLPCPGSSVLMWS
DQLER
 FRAGMENT NO

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Scaffold:
TYPE Muskelin REFERENCES 11006128

Coupling with G-proteins:
Family:Gi/o REFERENCES:11095474
1GPR0026Galpha-o-Rattus norvegicus
2GPR0111Galpha-i3-Rattus norvegicus
3GPR0221Galpha-i1-Rattus norvegicus
4GPR0229Galpha-i2-Rattus norvegicus
Family:Gq/11 REFERENCES:11095474
5GPR0032Galpha-11-Rattus norvegicus
6GPR0242Galpha-q-Rattus norvegicus
Family:Gs REFERENCES:11095474
7GPR0124Galpha-s-Rattus norvegicus-2
8GPR0392Galpha-s-Rattus norvegicus-1

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athina University of Athens
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 Dept. of Cell Biology and Biophysics
Biophysics
& Bioinformatics
Laboratory