gpDB: a database of GPCRs, G-proteins, Effectors and their interactions
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gpDB::GPCR View
Entry 1 of 1 :: GPCR0815 ::
CLASS CLASS A (RHODOPSIN LIKE)
FAMILY ENDOTHELIN RECEPTOR
SUBFAMILY ET-A

Cross References:
UniProt Q61614 | O54993 | Q91VV2 EMBL AK043210 | BC008277 | AF039892 | L20340
InterPro IPR000499 | IPR002175 | IPR000276 GPCRDB EDNRA_MOUSE
GENEID 13617
PRINTS PR00570 | PR00366 | PR00237 PFAM PF00001

Details:
NAME ENDOTHELIN RECEPTOR_ET-A_Mus musculus
DESCRIPTION Endothelin-1 receptor precursor (Endothelin A receptor) (ET-A) (ET-AR).
SPECIES Mus musculus COMMON NAME Mouse NCBI Taxonomy 10090
GENE Ednra | Gpcr10
SEQUENCE
MSIFCLAAYFWLTMVGGVMADNPERYSANLSSHMEDFTPFPGTEINFLGTTHRPPNLALP
SNGSMHGYCPQQTKITTAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIA
SLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALS
VDRYRAVASWSRVQGIGIPLITAIEIVSIWILSFILAIPEAIGFVMVPFEYKGELHRTCM
LNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQ
RREVAKTVFCLVVIFALCWFPLHLSRILKKTVYDEMDKNRCELLSFLLLMDYIGINLATM
NSCINPIALYFVSKKFKNCFQSCLCCCCHQSKSLMTSVPMNGTSIQWKNQEQNNHNTERS
SHKDSMN
FRAGMENT NO

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Scaffold:
TYPE beta-arrestin-1 - 2 REFERENCES 11546805

Coupling with G-proteins:
Family:G12/13 REFERENCES:10364236
1GPR0035Galpha-12-Mus musculus
2GPR0038Galpha-13-Mus musculus-2
3GPR0323Galpha-13-Mus musculus-3
4GPR0380Galpha-13-Mus musculus-1
Family:Gq/11 REFERENCES:1849646
5GPR0031Galpha-11-Mus musculus-2
6GPR0240Galpha-q-Mus musculus
7GPR0360Galpha-11-Mus musculus-1
Family:Gs REFERENCES:1849646
8GPR0123Galpha-s-Mus musculus-2
9GPR0391Galpha-s-Mus musculus


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athina University of Athens
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Dept. of Cell Biology and Biophysics
Biophysics
& Bioinformatics
Laboratory